SARS-CoV-2 mutations and their impact on diagnostics, therapeutics and vaccines

S Thakur, S Sasi, SG Pillai, A Nag, D Shukla… - Frontiers in …, 2022 - frontiersin.org
With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2
variants was inevitable. Several mutations have been identified in the SARS-CoV-2 …

Nucleic acid vaccines for COVID-19: a paradigm shift in the vaccine development arena

VP Chavda, MK Hossain, J Beladiya, V Apostolopoulos - Biologics, 2021 - mdpi.com
Coronavirus disease, COVID-19, has touched every country globally except five countries
(North Korea, Turkmenistan, Tonga, Tuvalu and Nauru). Vaccination is the most effective …

Efficacy and safety of the CVnCoV SARS-CoV-2 mRNA vaccine candidate in ten countries in Europe and Latin America (HERALD): a randomised, observer-blinded …

PG Kremsner, RAA Guerrero, E Arana-Arri… - The Lancet Infectious …, 2022 - thelancet.com
Background Additional safe and efficacious vaccines are needed to control the COVID-19
pandemic. We aimed to analyse the efficacy and safety of the CVnCoV SARS-CoV-2 mRNA …

COVID-19 and pregnancy: clinical outcomes; mechanisms, and vaccine efficacy

D Kumar, S Verma, IU Mysorekar - Translational Research, 2023 - Elsevier
As the COVID-19 pandemic continues into its third year, emerging data indicates increased
risks associated with SARS-CoV-2 infection during pregnancy, including pre-eclampsia …

COVID-19 and vaccination: myths vs science

VP Chavda, Y Chen, J Dave, ZS Chen… - Expert Review of …, 2022 - Taylor & Francis
Introduction Several vaccines against severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been developed since the inception of the coronavirus disease 2019 …

based biosensors for COVID-19: a review of innovative tools for controlling the pandemic

T Pinheiro, AR Cardoso, CEA Sousa, AC Marques… - ACS …, 2021 - ACS Publications
The appearance and quick spread of the new severe acute respiratory syndrome
coronavirus disease, COVID-19, brought major societal challenges. Importantly, suitable …

Investigation of statistical machine learning models for COVID-19 epidemic process simulation: Random forest, K-nearest neighbors, gradient boosting

D Chumachenko, I Meniailov, K Bazilevych… - Computation, 2022 - mdpi.com
COVID-19 has become the largest pandemic in recent history to sweep the world. This study
is devoted to developing and investigating three models of the COVID-19 epidemic process …

An overview of current drugs and prophylactic vaccines for coronavirus disease 2019 (COVID-19)

A Alagheband Bahrami, A Azargoonjahromi… - Cellular & molecular …, 2022 - Springer
Designing and producing an effective vaccine is the best possible way to reduce the burden
and spread of a disease. During the coronavirus disease 2019 (COVID-19) pandemic, many …

Modeling the effect of the vaccination campaign on the COVID-19 pandemic

M Angeli, G Neofotistos, M Mattheakis… - Chaos, Solitons & …, 2022 - Elsevier
Population-wide vaccination is critical for containing the SARS-CoV-2 (COVID-19) pandemic
when combined with restrictive and prevention measures. In this study we introduce SAIVR …

Discovery and evaluation of entry inhibitors for SARS-CoV-2 and its emerging variants

A Acharya, K Pandey, M Thurman, E Klug… - Journal of …, 2021 - Am Soc Microbiol
The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
responsible for the coronavirus disease 19 (COVID-19) pandemic. Despite unprecedented …