Spermatogonial stem cells (SSCs) are crucial for maintaining spermatogenesis throughout
life, and understanding how these cells function has important implications for …

Spermatogenesis is a complex biological process of cellular transformation that produces
male haploid germ cells from diploid spermatogonial stem cells. This process has been …

This review addresses current understanding of the germline stem cell niche unit in
mammalian testes. Spermatogenesis is a classic model of tissue-specific stem cell function …

Two major functions of the mammalian ovary are the production of germ cells (oocytes),
which allow continuation of the species, and the generation of bioactive molecules, primarily …

Spermatogonial stem cells (SSCs) are the most primitive spermatogonia in the testis and
have an essential role to maintain highly productive spermatogenesis by self-renewal and …

This article will provide an updated review of spermatogonial stem cells and their role in
maintaining the spermatogenic lineage. Experimental tools used to study spermatogonial …

Spermatogenesis originates from spermatogonial stem cells (SSCs). Development of the
spermatogonial transplantation technique in 1994 provided the first functional assay to …

Mammalian spermatogenesis is a classic adult stem cell–dependent process, supported by
self-renewal and differentiation of spermatogonial stem cells (SSCs). Studying SSCs …

Context Young boys treated with high-dose chemotherapy are often confronted with infertility
once they reach adulthood. Cryopreserving testicular tissue before chemotherapy and …

Spermatogonial stem cells (SSCs) are the foundation for spermatogenesis and, thus,
preservation of a species. Because of stem cell rarity, studying their self-renewal is greatly …