The management of chronic rhinosinusitis with nasal polyps (CRSwNP) with biologics

A Wautlet, C Bachert, M Desrosiers, PW Hellings… - The Journal of Allergy …, 2023 - Elsevier
Chronic rhinosinusitis with nasal polyps affects a significant portion of the worldwide
population. This illness is associated with several chronic conditions and has an important …

[HTML][HTML] The Role of the Gut and Airway Microbiota in Chronic Rhinosinusitis with Nasal Polyps: A Systematic Review

M Gómez-García, E Moreno-Jimenez… - International Journal of …, 2024 - mdpi.com
In recent years, there has been growing interest in understanding the potential role of
microbiota dysbiosis or alterations in the composition and function of human microbiota in …

Causal analysis between gastroesophageal reflux disease and chronic rhinosinusitis

G Chen, W Guo, S Liu, Y Wang, X Zhang - European Archives of Oto …, 2024 - Springer
Background Gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS)
have been shown to be potentially closely related, but the relationship between these …

Exploring the latest understanding on the role of immune mediators, genetic and environmental factors in pathogenesis of allergic rhinitis: a systematic review

S Albloushi, M Al-Ahmad - Frontiers in Allergy, 2023 - frontiersin.org
Introduction Despite well-defined clinical phenotypes of chronic rhinitis, the underlying in-
depth pathophysiological mechanism, particularly with reference to the involvement of …

Comprehensive analysis of mitophagy-related genes in diagnosis and heterogeneous endothelial cells in chronic rhinosinusitis: based on bulk and single-cell RNA …

S Zhou, K Fan, J Lai, S Tan, Z Zhang, J Li, X Xu… - Frontiers in …, 2023 - frontiersin.org
Background: Chronic rhinosinusitis (CRS) is a complex inflammatory disorder affecting the
nasal and paranasal sinuses. Mitophagy, the process of selective mitochondrial degradation …

Metabolic syndrome facilitates histopathological changes and the risk of postoperative recurrence in chronic rhinosinusitis with nasal polyps

T Jiang, T Yu, L Jiang, M Qin, Z Tong - International Immunopharmacology, 2024 - Elsevier
Background The relationship between metabolic syndrome (MS) and chronic rhinosinusitis
with nasal polyps (CRSwNP) remains unclear. This study aimed to examine the effects of …

[HTML][HTML] Mucosal Inflammatory Memory in Chronic Rhinosinusitis

MS Koo, S Moon, MS Rha - Cells, 2024 - pmc.ncbi.nlm.nih.gov
Recent advancements in medical management, endoscopic sinus surgery, and biologics
have significantly improved outcomes for patients with chronic rhinosinusitis (CRS) …

Global Incidence and Prevalence of Chronic Rhinosinusitis: A Systematic Review

HK Min, S Lee, S Kim, Y Son, J Park… - Clinical & …, 2025 - Wiley Online Library
Objective Data on the global prevalence of chronic rhinosinusitis (CRS) is significantly
varied and limited across countries and over time. Therefore, we aimed to conduct a …

Insights into the epigenetics of chronic rhinosinusitis with and without nasal polyps: a systematic review

T Brar, L Marks, D Lal - Frontiers in Allergy, 2023 - frontiersin.org
Background Epigenetics facilitates insights on the impact of host environment on the
genesis of chronic rhinosinusitis (CRS) through modulations of host gene expression and …

Aspirin-exacerbated respiratory disease is associated with variants in filaggrin, epithelial integrity, and cellular interactions

E Jerschow, R Dubin, CC Chen, E Sehanobish… - Journal of Allergy and …, 2024 - Elsevier
Background Previous studies have determined that up to 6% of patients with aspirin-
exacerbated respiratory disease (AERD) have family history of AERD, indicating a possible …