Executive summary Traumatic brain injury (TBI) has the highest incidence of all common
neurological disorders, and poses a substantial public health burden. TBI is increasingly …

The scope and purpose of this work is 2-fold: to synthesize the available evidence and to
translate it into recommendations. This document provides recommendations only when …

Objectives: A relationship between reduced brain tissue oxygenation and poor outcome
following severe traumatic brain injury has been reported in observational studies. We …

Neurocritical care depends, in part, on careful patient monitoring but as yet there are little
data on what processes are the most important to monitor, how these should be monitored …

Executive summary A concerted effort to tackle the global health problem posed by traumatic
brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently …

Traumatic brain injury (TBI) remains a significant source of death and permanent disability,
contributing to nearly one-third of all injury related deaths in the United States and exacting …

Intracranial pressure (ICP) monitoring is a staple of neurocritical care. The most commonly
used current methods of monitoring in the acute setting include fluid-based systems …

Importance While the relationship between persistent elevations in intracranial pressure
(ICP) and poorer outcomes is well established for patients with traumatic brain injury (TBI) …

Several experimental studies have provided evidence that bone-marrow derived
mesenchymal stem (stromal) cells (MSC) may be effective in treating critically ill surgical …

Intracranial pressure (ICP) measurements are essential in evaluation and treatment of
neurological disorders such as subarachnoid and intracerebral hemorrhage, ischemic …