Local antibiotic delivery options in prosthetic joint infection
Prosthetic Joint Infection (PJI) causes significant morbidity and mortality for patients globally.
Delivery of antibiotics to the site of infection has potential to improve the treatment outcomes …
Delivery of antibiotics to the site of infection has potential to improve the treatment outcomes …
Analysis of linezolid and tigecycline as candidates for local prophylaxis via antibiotic-loaded bone cement
T Nichol, TJ Smith, R Townsend… - Journal of …, 2016 - academic.oup.com
Objectives To assess the Gram-positive-specific antibiotic linezolid and the broad-spectrum
antibiotic tigecycline for use in local antibiotic delivery via antibiotic-loaded bone cement …
antibiotic tigecycline for use in local antibiotic delivery via antibiotic-loaded bone cement …
The cement spacer with multiple indentations: increasing antibiotic elution using a cement spacer 'teabag'
S Salih, A Paskins, T Nichol, T Smith… - The Bone & Joint …, 2015 - boneandjoint.org.uk
We investigated whether the indentation of bone cement spacers used in revision of infected
joint arthroplasty with a MacDonald dissector increased the elution of antibiotic in vitro. A …
joint arthroplasty with a MacDonald dissector increased the elution of antibiotic in vitro. A …
Influencia de cefazolina y vancomicina en la resistencia al desgaste del cemento óseo
Objetivo: Evaluar experimentalmente la influencia de la mezcla de dos antibióticos,
vancomicina y cefazolina, sobre la resistencia al desgaste del cemento óseo (PMMA) …
vancomicina y cefazolina, sobre la resistencia al desgaste del cemento óseo (PMMA) …
PMMA and Antimicrobial Delivery
AC McLaren, CS Estes, R McLemore - … Joint Infection of the Hip and Knee, 2013 - Springer
Acrylic bone cement, poly (methyl methacrylate)(PMMA), is an acrylic polymer used in
orthopedic surgery primarily to fix prosthetic implants in bone. Since the early 1950s, cement …
orthopedic surgery primarily to fix prosthetic implants in bone. Since the early 1950s, cement …