The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers

I Cavallari, F Ciccarese, E Sharova, L Urso… - Cancers, 2021 - mdpi.com
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …

Inflammatory breast cancer biology: the tumour microenvironment is key

B Lim, WA Woodward, X Wang, JM Reuben… - Nature Reviews …, 2018 - nature.com
Inflammatory breast cancer (IBC) is a rare and aggressive disease that accounts for~ 2–4%
of all breast cancers. However, despite its low incidence rate, IBC is responsible for 7–10 …

YTHDF3 induces the translation of m6A-enriched gene transcripts to promote breast cancer brain metastasis

G Chang, L Shi, Y Ye, H Shi, L Zeng, S Tiwary, JT Huse… - Cancer cell, 2020 - cell.com
Brain metastasis is a major cause of cancer mortality, but its molecular mechanisms are
severely understudied. In addition, little is known regarding the role of m 6 A reader YTHDF3 …

Preclinical development of a microRNA-based therapy for intervertebral disc degeneration

M Ji, H Jiang, X Zhang, P Shi, C Li, H Wu, X Wu… - Nature …, 2018 - nature.com
Understanding the molecular mechanisms regulating the maintenance and destruction of
intervertebral disc may lead to the development of new therapies for intervertebral disc …

MiRNA and LncRNA as potential biomarkers in triple-negative breast cancer: a review

SR Volovat, C Volovat, I Hordila, DA Hordila… - Frontiers in …, 2020 - frontiersin.org
Noncoding RNAs (ncRNAs) include a diverse range of RNA species, including microRNAs
(miRNAs) and long noncoding RNAs (lncRNAs). MiRNAs, ncRNAs of approximately 19–25 …

Regulation of breast cancer metastasis signaling by miRNAs

BJ Petri, CM Klinge - Cancer and metastasis reviews, 2020 - Springer
Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Potential miRNA use as a biomarker: from breast cancer diagnosis to metastasis

E Jordan-Alejandre, AD Campos-Parra… - Cells, 2023 - mdpi.com
Breast cancer is the most common cancer in women. Despite advances in diagnosis and
prognosis, distal metastases occur in these patients in up to 15% of cases within 3 years of …

Brain metastasis cell lines panel: a public resource of organotropic cell lines

M Valiente, AED Van Swearingen, CK Anders… - Cancer research, 2020 - AACR
Spread of cancer to the brain remains an unmet clinical need in spite of the increasing
number of cases among patients with lung, breast cancer, and melanoma most notably …

Interplay between p53 and non-coding RNAs in the regulation of EMT in breast cancer

S Parfenyev, A Singh, O Fedorova, A Daks… - Cell death & …, 2021 - nature.com
The epithelial–mesenchymal transition (EMT) plays a pivotal role in the differentiation of
vertebrates and is critically important in tumorigenesis. Using this evolutionarily conserved …

MicroRNA-200c and microRNA-141 are regulated by a FOXP3-KAT2B axis and associated with tumor metastasis in breast cancer

G Zhang, W Zhang, B Li, E Stringer-Reasor, C Chu… - Breast cancer …, 2017 - Springer
Background Members of the microRNA (miR)-200 family, which are involved in tumor
metastasis, have potential as cancer biomarkers, but their regulatory mechanisms remain …