Microtechnology-based methods for organoid models

V Velasco, SA Shariati, R Esfandyarpour - Microsystems & …, 2020 - nature.com
Innovations in biomaterials and stem cell technology have allowed for the emergence of
novel three-dimensional (3D) tissue-like structures known as organoids and spheroids. As a …

Bone tissue engineering for treating osteonecrosis of the femoral head

Y Bian, T Hu, Z Lv, Y Xu, Y Wang, H Wang, W Zhu… - …, 2023 - Wiley Online Library
Osteonecrosis of the femoral head (ONFH) is a devastating and complicated disease with an
unclear etiology. Femoral head‐preserving surgeries have been devoted to delaying and …

Cell‐based delivery systems: emerging carriers for immunotherapy

Z Li, Y Wang, Y Ding, L Repp… - Advanced Functional …, 2021 - Wiley Online Library
Immunotherapy is leading a paradigm shift in the treatment of various diseases, including
tumors, auto‐immune diseases, and infectious diseases. However, the limited response rate …

Muscle tissue engineering in fibrous gelatin: implications for meat analogs

LA MacQueen, CG Alver, CO Chantre, S Ahn… - npj Science of …, 2019 - nature.com
Bioprocessing applications that derive meat products from animal cell cultures require food-
safe culture substrates that support volumetric expansion and maturation of adherent muscle …

Mechanical properties of materials for stem cell differentiation

SB Han, JK Kim, G Lee, DH Kim - Advanced Biosystems, 2020 - Wiley Online Library
Recent findings about cell fate change induced by physical stimuli have expedited the
discovery of underlying regulatory mechanisms that determine stem cell differentiation …

Multifunctional DNA hydrogel enhances stemness of adipose‐derived stem cells to activate immune pathways for guidance burn wound regeneration

L Zhou, Z Zeng, S Liu, T Min, W Zhang… - Advanced Functional …, 2022 - Wiley Online Library
A grade 3 burn is a nonstatic fatal injury, which can lead to complete damage to the skin
structure, accompanied by a series of symptoms such as persistent inflammation, pain …

Materials for cell surface engineering

K Adebowale, R Liao, VC Suja, N Kapate… - Advanced …, 2024 - Wiley Online Library
Cell therapies are emerging as a promising new therapeutic modality in medicine,
generating effective treatments for previously incurable diseases. Clinical success of cell …

Single-cell RNA sequencing: technological progress and biomedical application in cancer research

X Chang, Y Zheng, K Xu - Molecular Biotechnology, 2024 - Springer
Single-cell RNA-seq (scRNA-seq) is a revolutionary technology that allows for the genomic
investigation of individual cells in a population, allowing for the discovery of unusual cells …

Programmable synthetic receptors: the next-generation of cell and gene therapies

F Teng, T Cui, L Zhou, Q Gao, Q Zhou… - Signal Transduction and …, 2024 - nature.com
Cell and gene therapies hold tremendous promise for treating a range of difficult-to-treat
diseases. However, concerns over the safety and efficacy require to be further addressed in …

[HTML][HTML] Context-aware synthetic biology by controller design: Engineering the mammalian cell

N Shakiba, RD Jones, R Weiss, D Del Vecchio - Cell systems, 2021 - cell.com
The rise of systems biology has ushered a new paradigm: the view of the cell as a system
that processes environmental inputs to drive phenotypic outputs. Synthetic biology provides …