Transformation of SH-SY5Y cell line into neuron-like cells: Investigation of electrophysiological and biomechanical changes

M Şahin, G Öncü, MA Yılmaz, D Özkan, H Saybaşılı - Neuroscience Letters, 2021 - Elsevier
Abstract SH-SY5Y human neuroblastoma cells are commonly used as neuronal models.
Here, we examined different aspects of SH-SY5Y cell differentiation. Various differentiation …

Changes in biophysical properties of undifferentiated SH-SY5Y cells during long-term cultures

S Santillo - Neuroscience, 2022 - Elsevier
The electrophysiological properties of undifferentiated SH-SY5Y cells were examined during
cultures prolonged even to 20 days by measuring the passive and active membrane …

Perspectives on Scaffold Designs with Roles in Liver Cell Asymmetry and Medical and Industrial Applications by Using a New Type of Specialized 3D Bioprinter

I Harbuz, DD Banciu, R David, C Cercel… - International Journal of …, 2023 - mdpi.com
Cellular asymmetry is an important element of efficiency in the compartmentalization of
intracellular chemical reactions that ensure efficient tissue function. Improving the current 3D …

Degree of differentiation impacts neurobiological signature and resistance to hypoxia of SH-SY5Y cells

EJHF Voogd, N Doorn, MR Levers… - Journal of neural …, 2024 - iopscience.iop.org
Objective. SH-SY5Y cells are valuable neuronal in vitro models for studying patho-
mechanisms and treatment targets in brain disorders due to their easy maintenance, rapid …

Substrate stiffness effects on SH‐SY5Y: the dichotomy of morphology and neuronal behavior

A Ozgun, FZ Erkoc‐Biradlı, O Bulut… - Journal of Biomedical …, 2021 - Wiley Online Library
Like many other cell types, neuroblastoma cells are also known to respond to mechanical
cues in their microenvironment in vitro. They were shown to have mechanotransduction …

Low cost SU-8 lift-off process to fabricate a gold/glass microelectrodes array for culturing applications

M Cabello, I Domínguez, C Macías… - Microsystem …, 2021 - Springer
In this paper, a procedure to release SU-8 layers from glass substrates using typical
undesirable effects is described. The proposed process can be used as lift off or stripping …

A Transient Survival Model of Alteration of Electrophysiological Properties Due to Amyloid Beta Toxicity Based on SH-SY5Y Cell Line

M Abbaszadeh, M Sahin, A Ozgun… - Current Alzheimer …, 2020 - ingentaconnect.com
Background: Accumulation of toxic strands of amyloid beta (AB), which cause neurofibrillary
tangles and, ultimately, cell death, is suspected to be the main culprit behind clinical …

Parkinson's disease: experimental in vitro model validation and the potential role of cofilin-1 in the pathophysiological mechanisms

FM Lopes - 2017 - lume.ufrgs.br
The dopaminergic neurodegeneration in the substantia nigra pars compacta (SNpc) is
responsible for the marked motor impairment observed in Parkinson's disease (PD) …

[引用][C] Biophysical approaches for modulating neural differentiation

A Özgün - 2021 - Thesis (Ph. D.)-Bogazici University …

[引用][C] MEMS-based Lab-on-chip platform with integrated 3D and planar microelectrodes for organotypic and cell cultures