Contraception technology: past, present and future

R Sitruk-Ware, A Nath, DR Mishell Jr - Contraception, 2013 - Elsevier
Steady progress in contraception research has been achieved over the past 50 years.
Hormonal and nonhormonal modern contraceptives have improved women's lives by …

The evolution of combined oral contraception: improving the risk-to-benefit ratio

R Burkman, C Bell, D Serfaty - Contraception, 2011 - Elsevier
Since its introduction in 1960, the combined oral contraceptive (COC) pill has become one
of the most widely and frequently used methods of contraception worldwide. Although highly …

Drug-eluting fibers for HIV-1 inhibition and contraception

C Ball, E Krogstad, T Chaowanachan, KA Woodrow - PloS one, 2012 - journals.plos.org
Multipurpose prevention technologies (MPTs) that simultaneously prevent sexually
transmitted infections (STIs) and unintended pregnancy are a global health priority …

ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study

AR Thurman, TR Moench, M Hoke, JA Politch… - American journal of …, 2023 - Elsevier
Background With an unplanned pregnancy rate of 50% or more in many countries, there is
an urgent need for contraceptives that are more accessible and acceptable. To meet the …

Women's preferences and acceptance for different drug delivery routes and products

R Palmeira-de-Oliveira, AS Oliveira, J Rolo… - Advanced Drug Delivery …, 2022 - Elsevier
To use or not to use, that is the first decision to take regarding a drug product. This
mandatory step for adherence dictates product efficacy. The determinants for such decision …

On the determining role of network structure titania in silicone against bacterial colonization: mechanism and disruption of biofilm

D Depan, RDK Misra - Materials Science and Engineering: C, 2014 - Elsevier
Silicone-based biomedical devices are prone to microbial adhesion, which is the primary
cause of concern in the functioning of the artificial device. Silicone exhibiting long-term and …

Vaginal rings for delivery of HIV microbicides

RK Malcolm, SM Fetherston, CF McCoy… - … Journal of Women's …, 2012 - Taylor & Francis
Following the successful development of long-acting steroid-releasing vaginal ring devices
for the treatment of menopausal symptoms and contraception, there is now considerable …

Engineering monoclonal antibody-based contraception and multipurpose prevention technologies

DJ Anderson, JA Politch, RA Cone… - Biology of …, 2020 - academic.oup.com
Sexually transmitted infections are highly prevalent, and over 40% of pregnancies are
unplanned. We are producing new antibody-based multipurpose prevention technology …

How much demand for new HIV prevention technologies can we really expect? Results from a discrete choice experiment in South Africa

F Terris-Prestholt, K Hanson, C MacPhail, P Vickerman… - PloS one, 2013 - journals.plos.org
Background For the first time in the history of HIV, new bio-medical interventions have been
shown to be effective in preventing HIV transmission. For these new HIV prevention …

Multipurpose prevention technologies: products in development

DR Friend, JT Clark, PF Kiser, MR Clark - Antiviral research, 2013 - Elsevier
Multipurpose prevention technologies (MPTs) are broadly defined as products capable of
simultaneously addressing multiple sexual and reproductive health needs including …