Age-related neurological disorders continue to pose a significant societal and economic
burden. Aging is a complex phenomenon that affects many aspects of the human body …

The predilection site of intracerebral hemorrhage (ICH) is in the basal ganglia, which is rich
in white matter (WM) fiber bundles, such as cerebrospinal tract in the internal capsule. ICH …

Traumatic brain injury (TBI) patients often exhibit slowed information processing speed that
can underlie diverse symptoms. Processing speed depends on neural circuit function at …

Neuroinflammation plays important roles in the pathogenesis and progression of altered
neurodevelopment, sensorineural hearing loss, and certain neurodegenerative diseases …

Traumatic brain injury (TBI) has been recognized as one of the major public health issues
that leads to devastating neurological disability. As a consequence of primary and …

In this commentary we discuss International Stem Cell Corporation's (ISCO's) approach to
developing a pluripotent stem cell based treatment for Parkinson's disease (PD). In 2016 …

Following injury to the central nervous system, astrocytes perform critical and complex
functions that both promote and antagonize neural repair. Understanding the molecular …

Multiple Sclerosis (MS) causes neurologic disability due to inflammation, demyelination, and
neurodegeneration. Immunosuppressive treatments can modify the disease course but do …

Sonic hedgehog (Shh) signaling is a key pathway within the central nervous system (CNS),
during both development and adulthood, and its activation via the 7-transmembrane protein …

Neurological diseases in the central nervous system are mostly characterized by the failure
of endogenous repair to restore tissue damage and salvage lost function. Currently, studies …