JH Cole, K Franke - Trends in neurosciences, 2017 - cell.com
The brain changes as we age and these changes are associated with functional deterioration and neurodegenerative disease. It is vital that we better understand individual …
Recent critical commentaries unfavorably compare deep learning (DL) with standard machine learning (SML) approaches for brain imaging data analysis. However, their …
The brain-age paradigm is proving increasingly useful for exploring aging-related disease and can predict important future health outcomes. Most brain-age research uses structural …
As our brains age, we tend to experience cognitive decline and are at greater risk of neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases …
L Dye, NB Boyle, C Champ, C Lawton - Proceedings of the nutrition …, 2017 - cambridge.org
The relationship between obesity and cognitive impairment is important given the globally ageing population in whom cognitive decline and neurodegenerative disorders will carry …
ML Elliott, DW Belsky, AR Knodt, D Ireland… - Molecular …, 2021 - nature.com
An individual's brainAGE is the difference between chronological age and age predicted from machine-learning models of brain-imaging data. BrainAGE has been proposed as a …
Conditions and comorbidities of obesity mirror those of ageing and age‐related diseases. Obesity and ageing share a similar spectrum of phenotypes such as compromised genomic …
Ageing is commonly associated with changes to segregation and integration of functional brain networks, but, in isolation, current network-based approaches struggle to elucidate …
Context Chronic obesity is associated with several complications, including cognitive impairment and dementia. However, we have only piecemeal knowledge of the mechanisms …