Abstract The European Cooperation in Science and Technology (COST) provides an ideal
framework to establish multi-disciplinary research networks. COST Action BM1203 (EU …

Review on the ability of different TLR agonists to orchestrate antitumor immune responses,
or promote tumor growth, underscoring the impact of choosing among TLR agonists when …

Oral squamous cell carcinoma (OSCC) is a lethal disease whose incidence is increasing.
Epidemiologic studies demonstrate an association between periodontitis and oral cancer …

Although the discovery and characterization of multiple tumor antigens have sparked the
development of many antigen/derived cancer vaccines, many are poorly immunogenic and …

Toll-like receptors (TLRs) are a family of transmembrane receptors that recognize various
pathogen-and damage-associated molecular pattern molecules playing an important role in …

Toll-like receptors (TLRs) play a crucial role in the innate immune response and the
subsequent induction of adaptive immune responses against microbial infection or tissue …

Toll-like receptors (TLRs) belong to a class of pattern-recognition receptors that play an
important role in host defense against pathogens by recognizing a wide variety of pathogen …

Abstract The activator protein-1 (AP-1) family of transcription factors modulate a diverse
range of cellular signalling pathways into outputs which can be oncogenic or anti …

Background: The Toll-like receptor (TLR) 4 signalling pathway has been shown to have
oncogenic effects in vitro and in vivo. To demonstrate the role of TLR4 signalling in colon …

Due to the rapid increase of new information on the multiple roles of Toll-like receptors
(TLRs), this paper reviews several main properties of TLRs and their ligands and signaling …