It has long been considered that the oral microbiome is tightly connected to oral health and
that dysbiotic changes can be detrimental to the occurrence and progression of dysplastic …

The intratumoral microbiome (TM) refers to the microorganisms in the tumor tissues,
including bacteria, fungi, viruses, and so on, and is distinct from the gut microbiome and …

Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the head
and neck region, and its treatment is limited by hypoxia and inadequate oxygen supply …

Oral squamous cell carcinoma (OSCC) is a prevalent oral malignancy, which poses
significant health risks with a high mortality rate. Regulatory T cells (Tregs), characterized by …

Lactate and its derivative, lactylation, play pivotal roles in modulating immune responses
within the tumor microenvironment (TME), particularly in T-cell-mediated cancer …

Oral squamous cell carcinoma (OSCC) is a highly aggressive and malignant tumor of oral
cavity with a poor prognosis and high mortality due to the limitations of existing therapies …

Backgrounds Gastric cancer (GC) remains a global health threat due to frequent treatment
failures caused by primary or acquired resistance. Although cancer-associated fibroblasts …

Background The high prevalence and detrimental effects on patient outcomes make gastric
cancer (GC) a significant health issue that persists internationally. Existing treatment …

Oral squamous cell carcinoma (OSCC) is an increasingly prevalent malignancy worldwide.
This study aims to understand molecular alterations associated with lymph node metastasis …