Targeting steroid receptor coactivators in cancer via small molecule agents
Steroid receptor coactivators (SRCs) are a family of nuclear receptor (NR) coregulators
comprised of three evolutionarily related, yet distinct proteins SRC-1, SRC-2 and SRC-3 …
comprised of three evolutionarily related, yet distinct proteins SRC-1, SRC-2 and SRC-3 …
Discovery of novel 2, 4-diarylaminopyrimidine hydrazone derivatives as potent anti-thyroid cancer agents capable of inhibiting FAK
H Li, MQ Jia, ZL Qin, C Lu, W Chu, Z Zhang… - Journal of Enzyme …, 2024 - Taylor & Francis
Abstract In this work, thirty 2, 4-diarylaminopyrimidine-based hydrazones were designed,
synthesised, and their anti-thyroid cancer activity were explored. The majority of compounds …
synthesised, and their anti-thyroid cancer activity were explored. The majority of compounds …