[HTML][HTML] Advances and trends in omics technology development

X Dai, L Shen - Frontiers in Medicine, 2022 - frontiersin.org
The human history has witnessed the rapid development of technologies such as high-
throughput sequencing and mass spectrometry that led to the concept of 'omics' and …

[HTML][HTML] From Genes to Clinical Practice: Exploring the Genomic Underpinnings of Endometrial Cancer

T Molefi, L Mabonga, R Hull, M Sebitloane, Z Dlamini - Cancers, 2025 - mdpi.com
Endometrial cancer (EC), a prevalent gynecological malignancy, presents significant
challenges due to its genetic complexity and heterogeneity. The genomic landscape of EC is …

Detection of driver mutations and genomic signatures in endometrial cancers using artificial intelligence algorithms

A Stan, K Bosart, M Kaur, M Vo, W Escorcia, RJ Yoder… - Plos one, 2024 - journals.plos.org
Analyzed endometrial cancer (EC) genomes have allowed for the identification of molecular
signatures, which enable the classification, and sometimes prognostication, of these …

HER2 Status Assessment in Endometrial Serous Carcinoma: comparative analysis of two proposed testing and interpretation algorithms

S Hashem, SY Zare, O Fadare - International Journal of …, 2024 - journals.lww.com
HER2 status is now routinely assessed in endometrial serous carcinoma (ESC) due to the
reported predictive value of HER2 protein overexpression and/or gene amplification. Herein …

High RIG-I and EFTUD2 expression predicts poor survival in endometrial cancer

S Beyer, L Müller, S Mitter, L Keilmann… - Journal of Cancer …, 2023 - Springer
Purpose Endometrial cancer is the most common gynecological malignancy. The helicase
RIG-I, a part of the innate immune system, and EFTUD2, a splicing factor which can …

[HTML][HTML] Molecular classification of endometrial cancer: entering an era of precision medicine

A Goulder, SL Gaillard - Journal of Gynecologic Oncology, 2022 - ncbi.nlm.nih.gov
[4, 5]. Finally, tumors with NSMP—in essence, those tumors who do not fall into any of the
other 3 groups—tend to have endometrioid histology and are frequently estrogen …

p53 Immunohistochemical Staining and TP53 Gene Mutations in Endometrial Cancer: Does Null Pattern Correlate With Prognosis?

I Sakamoto, K Kagami, T Nozaki, Y Hirotsu… - The American journal …, 2023 - journals.lww.com
Whether immunohistochemistry (IHC) of p53 accurately reflects the TP53 mutational status
of endometrial carcinoma (EC) has not yet been established. This study aimed to clarify the …

[HTML][HTML] Post-surgical ctDNA-based molecular residual disease detection in patients with stage I uterine malignancies

F Recio, CB Scalise, P Loar, M Lumish, T Berman… - Gynecologic …, 2024 - Elsevier
Introduction Among uterine malignancies, endometrial cancer (EC) is the most common
cancer of the female reproductive tract. Traditionally, risk stratification in EC is determined by …

Advances in Molecular and Genetic Technologies and the Problems Related to Their Application in Personalized Medicine

V Nakhod, A Krivenko, T Butkova, K Malsagova… - Journal of Personalized …, 2024 - mdpi.com
Advances in the global personalized medicine market are directly related to innovations and
developments in molecular and genetic technologies. This review focuses on the key trends …

Clinical characterization and genomic landscape of gynecological cancers among patients attending a Chinese hospital

C Jiang, Y Lu, H Liu, G Cai, Z Peng, W Feng… - Frontiers in …, 2023 - frontiersin.org
Background Gynecological cancers are the most lethal malignancies among females, most
of which are associated with gene mutations. Few studies have compared the differences in …