Simple Summary Skeletal muscle mass is an important economic trait, and muscle
development and growth is a crucial factor to supply enough meat for human consumption …

Discovering the genetic basis of a Mendelian phenotype establishes a causal link between
genotype and phenotype, making possible carrier and population screening and direct …

INTRODUCTION The brain is responsible for cognition, behavior, and much of what makes
us uniquely human. The development of the brain is a highly complex process, and this …

The importance of gut microbiota in human health and pathophysiology is undisputable.
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …

The vast majority of coding variants are rare, and assessment of the contribution of rare
variants to complex traits is hampered by low statistical power and limited functional data …

MicroRNA targets are often recognized through pairing between the miRNA seed region
and complementary sites within target mRNAs, but not all of these canonical sites are …

Methods used to sequence the transcriptome often produce more than 200 million short
sequences. We introduce StringTie, a computational method that applies a network flow …

INTRODUCTION Resolving the molecular details of proteome variation in the different
tissues and organs of the human body would greatly increase our knowledge of human …

Maintenance of the blood system requires balanced cell fate decisions by hematopoietic
stem and progenitor cells (HSPCs). Because cell fate choices are executed at the individual …

Abstract Ensembl (www. ensembl. org) is a database and genome browser for enabling
research on vertebrate genomes. We import, analyse, curate and integrate a diverse …