TP53 Mutations in Head and Neck Squamous Cell Carcinoma and Their Impact on Disease Progression and Treatment Response
G Zhou, Z Liu, JN Myers - Journal of cellular biochemistry, 2016 - Wiley Online Library
Recent studies describing the mutational landscape of head and neck squamous cell
carcinoma (HNSCC) on a genomic scale by our group and others, including The Cancer …
carcinoma (HNSCC) on a genomic scale by our group and others, including The Cancer …
Cell cycle control and cancer
LH Hartwell, MB Kastan - Science, 1994 - science.org
Multiple genetic changes occur during the evolution of normal cells into cancer cells. This
evolution is facilitated in cancer cells by loss of fidelity in the processes that replicate, repair …
evolution is facilitated in cancer cells by loss of fidelity in the processes that replicate, repair …
Evidence for a causal association between human papillomavirus and a subset of head and neck cancers
ML Gillison, WM Koch, RB Capone… - Journal of the …, 2000 - academic.oup.com
Background: High-risk human papillomaviruses (HPVs) are etiologic agents for anogenital
tract cancers and have been detected in head and neck squamous cell carcinomas …
tract cancers and have been detected in head and neck squamous cell carcinomas …
Head and neck cancer
A Forastiere, W Koch, A Trotti… - New England Journal of …, 2001 - Mass Medical Soc
Head and neck cancers include neoplasms of the oral cavity, pharynx, and larynx. The risk
of these cancers is strongly associated with smoking and alcohol ingestion. There have …
of these cancers is strongly associated with smoking and alcohol ingestion. There have …
Levels of TGF-α and EGFR protein in head and neck squamous cell carcinoma and patient survival
JR Grandis, MF Melhem, WE Gooding… - JNCI: Journal of the …, 1998 - academic.oup.com
Background: The most accurate predictor of disease recurrence in patients treated for head
and neck squamous cell carcinoma is, at present, the extent of regional lymph node …
and neck squamous cell carcinoma is, at present, the extent of regional lymph node …
[HTML][HTML] Tumor microenvironment in head and neck squamous cell carcinoma
JM Curry, J Sprandio, D Cognetti, A Luginbuhl… - Seminars in …, 2014 - Elsevier
The tumor microenvironment (TME) of head and neck squamous cell carcinoma (HNSCC) is
comprised of cancer-associated fibroblasts (CAFs), immune cells, and other supporting …
comprised of cancer-associated fibroblasts (CAFs), immune cells, and other supporting …
Epidermal growth factor receptor biology in head and neck cancer
S Kalyankrishna, JR Grandis - Journal of clinical oncology, 2006 - ascopubs.org
Epidermal growth factor receptor (EGFR) is overexpressed in several epithelial
malignancies, including head and neck squamous cell carcinoma (HNSCC), which exhibits …
malignancies, including head and neck squamous cell carcinoma (HNSCC), which exhibits …
Molecular pathogenesis of oral squamous cell carcinoma: implications for therapy
S Choi, JN Myers - Journal of dental research, 2008 - journals.sagepub.com
The development of oral squamous cell carcinoma (OSCC) is a multistep process requiring
the accumulation of multiple genetic alterations, influenced by a patient's genetic …
the accumulation of multiple genetic alterations, influenced by a patient's genetic …
Oral cancer: risk factors and molecular pathogenesis
Introduction Oral cancer is one of the most common cancers and it constitutes a major health
problem particularly in developing countries. It is one of the leading causes of death …
problem particularly in developing countries. It is one of the leading causes of death …
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and …
ONYX-015 is an adenovirus with the E1B 55-kDa gene deleted, engineered to selectively
replicate in and lyse p53-deficient cancer cells while sparing normal cells. Although ONYX …
replicate in and lyse p53-deficient cancer cells while sparing normal cells. Although ONYX …