Epidemiological studies have provided compelling evidence that multiple sclerosis (MS) is a
rare complication of infection with the Epstein–Barr virus (EBV), a herpesvirus that infects …

Multiple sclerosis is a chronic inflammatory disease of the CNS that results from the interplay
between heritable and environmental factors. Mounting evidence from different fields of …

The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Immediately after entry into host cells, viruses are sensed by the innate immune system,
leading to the activation of innate antiviral effector mechanisms including the type I interferon …

The two human tumor viruses, Epstein–Barr virus (EBV) and Kaposi sarcoma-associated
herpesvirus (KSHV), have been mostly studied in isolation. Recent studies suggest that co …

Some lytic proteins encoded by Epstein-Barr virus (EBV) suppress host interferon (IFN)
signaling to facilitate viral replication. In this study, we sought to identify and characterize …

The Epstein-Barr virus (EBV) is a ubiquitous human pathogen linked to various diseases,
including infectious mononucleosis and multiple types of cancer. To control and eliminate …

ABSTRACT Epstein-Barr virus (EBV), a human herpesvirus, encodes 44 microRNAs
(miRNAs), which regulate many genes with various functions in EBV-infected cells. Multiple …

Plasmacytoid dendritic cells (pDCs) are a pioneer cell type that produces type I interferon
(IFN-I) and promotes antiviral immune responses. However, they are tolerogenic and, when …

Background Exposure to Epstein-Barr virus (EBV) infection has been hypothesized to be an
important risk factor for multiple rheumatic diseases, but the serological evidence so far for …