Harnessing the Power of Sugar-Based Nanoparticles: A Drug-Free Approach to Enhance Immune Checkpoint Inhibition against Glioblastoma and Pancreatic Cancer

FT Hsu, YT Chen, YC Chin, LC Chang, SC Chiang… - ACS …, 2024 - ACS Publications
Cancer cells have a high demand for sugars and express diverse carbohydrate receptors,
offering opportunities to improve delivery with multivalent glycopolymer materials. However …

Lysosome Targeting Chimaeras for Glut1-Facilitated Targeted Protein Degradation

J Luo, Q Gao, K Tan, S Zhang, W Shi… - Journal of the …, 2024 - ACS Publications
Targeted protein degradation technology holds great potential in biomedicine, particularly in
treating tumors and other protein-related diseases. Research on intracellular protein …

[HTML][HTML] Protocol to synthesize sequence-controlled glycooligomers for tumor targeting in mice

Q Lin, J Chen, Y Zhang, Q Gao, L Zhu, Q Xing, J Geng - STAR protocols, 2024 - Elsevier
Due to the higher and more rapid consumption of carbohydrates by cancer cells compared
to normal cells, carbohydrates can be effectively employed as a targeted therapeutic …