Modified Neuropixels probes for recording human neurophysiology in the operating room

B Coughlin, W Muñoz, Y Kfir, MJ Young, D Meszéna… - Nature …, 2023 - nature.com
Neuropixels are silicon-based electrophysiology-recording probes with high channel count
and recording-site density. These probes offer a turnkey platform for measuring neural …

Single-neuronal elements of speech production in humans

AR Khanna, W Muñoz, YJ Kim, Y Kfir, AC Paulk… - Nature, 2024 - nature.com
Humans are capable of generating extraordinarily diverse articulatory movement
combinations to produce meaningful speech. This ability to orchestrate specific phonetic …

Semantic encoding during language comprehension at single-cell resolution

M Jamali, B Grannan, J Cai, AR Khanna, W Muñoz… - Nature, 2024 - nature.com
From sequences of speech sounds, or letters, humans can extract rich and nuanced
meaning through language. This capacity is essential for human communication. Yet …

Large-scale high-density brain-wide neural recording in nonhuman primates

EM Trautmann, JK Hesse, GM Stine, R Xia, S Zhu… - BioRxiv, 2023 - biorxiv.org
High-density, integrated silicon electrodes have begun to transform systems neuroscience,
by enabling large-scale neural population recordings with single cell resolution. Existing …

Bypassing spike sorting: Density-based decoding using spike localization from dense multielectrode probes

Y Zhang, T He, J Boussard, C Windolf… - Advances in …, 2024 - proceedings.neurips.cc
Neural decoding and its applications to brain computer interfaces (BCI) are essential for
understanding the association between neural activity and behavior. A prerequisite for many …

[HTML][HTML] Ultra-high density electrodes improve detection, yield, and cell type identification in neuronal recordings

Z Ye, AM Shelton, JR Shaker, J Boussard, J Colonell… - bioRxiv, 2023 - ncbi.nlm.nih.gov
To understand the neural basis of behavior, it is essential to sensitively and accurately
measure neural activity at single neuron and single spike resolution. Extracellular …

DARTsort: A modular drift tracking spike sorter for high-density multi-electrode probes

J Boussard, C Windolf, C Hurwitz, HD Lee, H Yu… - bioRxiv, 2023 - biorxiv.org
With the advent of high-density, multi-electrode probes, there has been a renewed interest in
developing robust and scalable algorithms for spike sorting. Current spike sorting …

A Modular Implementation to Handle and Benchmark Drift Correction for High-Density Extracellular Recordings

S Garcia, C Windolf, J Boussard, B Dichter, AP Buccino… - Eneuro, 2024 - eneuro.org
High-density neural devices are now offering the possibility to record from neuronal
populations in vivo at unprecedented scale. However, the mechanical drifts often observed …

[HTML][HTML] DREDge: robust motion correction for high-density extracellular recordings across species

C Windolf, H Yu, AC Paulk, D Meszéna, W Muñoz… - bioRxiv, 2023 - ncbi.nlm.nih.gov
High-density microelectrode arrays (MEAs) have opened new possibilities for systems
neuroscience in human and non-human animals, but brain tissue motion relative to the array …