Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Generating the barriers that protect our inner surfaces from bacteria and other challenges
requires large glycoproteins called mucins. These come in two types, gel-forming and …

Protein posttranslational modifications (PTMs) refer to the breaking or generation of covalent
bonds on the backbones or amino acid side chains of proteins and expand the diversity of …

Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

Glycosylation is the most abundant and diverse posttranslational modification of proteins.
While several types of glycosylation can be predicted by the protein sequence context, and …

Fc‐Fusion proteins represent a successful class of biopharmaceutical products, with already
13 drugs approved in the European Union and United States as well as three biosimilar …

Liquid-liquid phase separation (LLPS) has received significant attention in recent biological
studies. It refers to a phenomenon that biomolecule exceeds the solubility, condensates and …

Glycosylation is crucial in cellular metabolism and survival. Of interest is the role of N-linked
and O-linked glycans in disease states. Robust analytical methods must be defined to …

Site-specific structural characterization of glycoproteins is important for understanding the
exact functional relevance of protein glycosylation. Resulting partly from the multiple layers …

Cholesterol homeostasis plays a significant role in cardiovascular disease. Previous studies
have indicated that ATP-binding cassette transporter A1 (ABCA1) is one of the most …