Recent progress in the development of fluorescent probes for imaging pathological oxidative stress

Y Geng, Z Wang, J Zhou, M Zhu, J Liu… - Chemical Society …, 2023 - pubs.rsc.org
Oxidative stress is closely related to the physiopathology of numerous diseases. Reactive
oxygen species (ROS), reactive nitrogen species (RNS), and reactive sulfur species (RSS) …

Recent advances in multifunctional fluorescent probes for viscosity and analytes

X Yang, D Zhang, Y Ye, Y Zhao - Coordination Chemistry Reviews, 2022 - Elsevier
Viscosity has become increasingly important in biological systems, especially as a major
factor in the process of diffusion control. The abnormality of viscosity is closely related to the …

Fluorescent probes for the detection of disease-associated biomarkers

WT Dou, HH Han, AC Sedgwick, GB Zhu, Y Zang… - Science Bulletin, 2022 - Elsevier
Fluorescent probes have emerged as indispensable chemical tools to the field of chemical
biology and medicine. The ability to detect intracellular species and monitor physiological …

Excited-state intramolecular proton-transfer (ESIPT) based fluorescence sensors and imaging agents

AC Sedgwick, L Wu, HH Han, SD Bull, XP He… - Chemical Society …, 2018 - pubs.rsc.org
In this review we will explore recent advances in the design and application of excited-state
intramolecular proton-transfer (ESIPT) based fluorescent probes. Fluorescence based …

Reaction-based fluorescent probes for the detection and imaging of reactive oxygen, nitrogen, and sulfur species

L Wu, AC Sedgwick, X Sun, SD Bull… - Accounts of chemical …, 2019 - ACS Publications
Conspectus This Account describes a range of strategies for the development of fluorescent
probes for detecting reactive oxygen species (ROS), reactive nitrogen species (RNS), and …

Dual-locked spectroscopic probes for sensing and therapy

L Wu, J Huang, K Pu, TD James - Nature Reviews Chemistry, 2021 - nature.com
Optical imaging probes allow us to detect and uncover the physiological and pathological
functions of an analyte of interest at the molecular level in a non-invasive, longitudinal …

Dual-channel fluorescent probe for the simultaneous monitoring of peroxynitrite and adenosine-5′-triphosphate in cellular applications

L Wu, J Liu, X Tian, RR Groleau, B Feng… - Journal of the …, 2021 - ACS Publications
Changes in adenosine triphosphate (ATP) and peroxynitrite (ONOO–) concentrations have
been correlated in a number of diseases including ischemia-reperfusion injury and drug …

NIRII‐HDs: A Versatile Platform for Developing Activatable NIR‐II Fluorogenic Probes for Reliable In Vivo Analyte Sensing

Z Qin, TB Ren, H Zhou, X Zhang, L He… - Angewandte Chemie …, 2022 - Wiley Online Library
Small‐molecule‐based second near‐infrared (NIR‐II) activatable fluorescent probes can
potentially provide a high target‐to‐background ratio and deep tissue penetration. However …

Photochromic fluorescent probe strategy for the super-resolution imaging of biologically important biomarkers

X Chai, HH Han, AC Sedgwick, N Li… - Journal of the …, 2020 - ACS Publications
Here, we report a β-galactosidase (β-Gal)-responsive photochromic fluorescent probe, NpG,
that was designed to prebind to human serum albumin (HSA) to form the probe/protein …

Indication of dynamic peroxynitrite fluctuations in the rat epilepsy model with a near-infrared two-photon fluorescent probe

X Luo, Z Cheng, R Wang, F Yu - Analytical Chemistry, 2021 - ACS Publications
Epilepsy is a chronic neurodegenerative disease that has seriously threatened human
health. Accumulating evidence reveals that the pathological progression of epilepsy is …