Effects of dexmedetomidine on patients undergoing radical gastrectomy

Y Wang, X Xu, H Liu, F Ji - journal of surgical research, 2015 - Elsevier
Background Surgical stress may cause immunosuppression especially in patients who have
surgery for primary tumor removed. This study aimed to explore the effects of …

Enhanced effect of κ-carrageenan on TNBS-induced inflammation in mice

W Wei, W Feng, G Xin, N Tingting, Z Zhanghe… - International …, 2016 - Elsevier
Background As a sulfated polysaccharide, carrageenan has been widely used as common
food additive. Methods In the present study, we investigated the effects of κ-carrageenan on …

Comparison of dexmedetomidine/fentanyl with midazolam/fentanyl combination for sedation and analgesia during tooth extraction

C Yu, S Li, F Deng, Y Yao, L Qian - International Journal of Oral and …, 2014 - Elsevier
Dexmedetomidine is an α2-adrenergic receptor agonist that causes minimal respiratory
depression compared with alternative drugs. This study investigated whether combined …

Dexmedetomidine alleviates intestinal barrier dysfunction and inflammatory response in mice via suppressing TLR4/MyD88/NF-κB signaling in an experimental model …

X Ye, H Xu, Y Xu - Folia Histochemica et Cytobiologica, 2022 - journals.viamedica.pl
Introduction. Ulcerative colitis (UC) is a nonspecific intestinal inflammatory disease.
Dexmedetomidine (DEX) is a selective alpha 2-adrenergic receptor agonist commonly used …

MFE40—the active fraction of Mume Fructus alcohol extract—alleviates Crohn's disease and its complications

Z Liu, Y Peng, L Zhao, X Li - Journal of Ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Mume Fructus (MF) is a well-known traditional
Chinese medicine used to treat chronic cough, prolonged diarrhea, and other inflammation …

Combined acupuncture and general anesthesia on immune and cognitive function in elderly patients following subtotal gastrectomy for gastric cancer

N Wang, Y Ou, W Qing - Oncology letters, 2018 - spandidos-publications.com
This study investigated the effects of acupuncture combined with general anesthesia on
postoperative immune and cognitive functions in elderly patients undergoing subtotal …

Effects of different methods of anesthesia and analgesia on immune function and serum tumor marker levels in critically ill patients

P Song, T Dong, J Zhang, J Li… - Experimental and …, 2017 - spandidos-publications.com
This study investigated the effects of different anesthesia and analgesia methods on immune
function and serum tumor marker levels of critically ill patients undergoing tumor resection …

Local level of TGF-β1 determines the effectiveness of dexamethasone through regulating the balance of Treg/Th17 cells in TNBS-induced mouse colitis

P You, N Chen, L Su, T Peng… - Experimental and …, 2018 - spandidos-publications.com
Transforming growth factor β1 (TGF-β1) has a crucial role in regulating the balance of type
17 T‑helper cells (Th17) and T regulatory cells (Tregs) that are involved in the pathogenesis …

Postoperative analgesic effect of dexmedetomidine combined with TPVB applied to open gastrectomy for gastric cancer

W Wan, Z Hou, Q Qiu - Immunopharmacology and …, 2023 - Taylor & Francis
Objectives This study is aimed to investigate the analgesic effect of combined
dexmedetomidine and thoracic paravertebral nerve block (TPVB) on gastric cancer (GC) …

Dexmedetomidine and regulation of splenic sympathetic nerve discharge

MJ Kenney, BT Larsen, RM McMurphy, D Mason… - Autonomic …, 2014 - Elsevier
Recent lines of inquiry indicate that sedatives can influence the immune system, leading to
the concept of sedative-induced immunomodulation. It has been hypothesized that …