QT prolongation, torsades de pointes, and psychotropic medications: a 5-year update

SR Beach, CM Celano, AM Sugrue, C Adams… - Psychosomatics, 2018 - Elsevier
Background Some psychotropic medications have been associated with prolongation of the
QT interval and QT prolongation, especially in those with medical illness, and are linked to …

A comparison of the risk of QT prolongation among SSRIs

KA Funk, JR Bostwick - Annals of Pharmacotherapy, 2013 - journals.sagepub.com
Objective: To report QT prolongation potential in selective serotonin reuptake inhibitors
(SSRIs) in order to advise clinicians on safe use of SSRIs other than citalopram in light of …

[HTML][HTML] DSM-5 criteria and depression severity: implications for clinical practice

JC Tolentino, SL Schmidt - Frontiers in psychiatry, 2018 - frontiersin.org
Background: Depression diagnosis requires five or more symptoms (Diagnostic and
Statistical Manual of Mental Disorders-DSM-5). One of them must be either Depressed mood …

[PDF][PDF] QT interval and antidepressant use: a cross sectional study of electronic health records

VM Castro, CC Clements, SN Murphy, VS Gainer… - Bmj, 2013 - bmj.com
Objective To quantify the impact of citalopram and other selective serotonin reuptake
inhibitors on corrected QT interval (QTc), a marker of risk for ventricular arrhythmia, in a large …

Guidelines for diagnosis and treatment of depression in older adults: a report from the Japanese Society of mood disorders

H Baba, S Kito, K Nukariya… - Psychiatry and …, 2022 - Wiley Online Library
The Committee for Treatment Guidelines of Mood Disorders, Japanese Society of Mood
Disorders, published a Japanese guideline for the treatment of late‐life depression in 2020 …

Antidepressant use and risk of cardiovascular outcomes in people aged 20 to 64: cohort study using primary care database

C Coupland, T Hill, R Morriss, M Moore, A Arthur… - bmj, 2016 - bmj.com
Objective To assess associations between different antidepressant treatments and rates of
three cardiovascular outcomes (myocardial infarction, stroke or transient ischaemic attack …

[HTML][HTML] Cardiovascular considerations in antidepressant therapy: an evidence-based review

H Yekehtaz, M Farokhnia… - The Journal of Tehran …, 2013 - ncbi.nlm.nih.gov
There is a definite correlation between cardiovascular diseases and depressive disorders.
Nevertheless, many aspects of this association have yet to be fully elucidated. Up to half of …

Antidepressant use in the elderly: the role of pharmacodynamics and pharmacokinetics in drug safety

J Sultana, E Spina, G Trifirò - Expert opinion on drug metabolism & …, 2015 - Taylor & Francis
Introduction: Antidepressants (ADs) are widely used among elderly persons, making AD-
related safety an important issue. Areas covered: This review highlights safety …

Risk of QT/QTc prolongation among newer non-SSRI antidepressants

NM Jasiak, JR Bostwick - Annals of Pharmacotherapy, 2014 - journals.sagepub.com
Objective: To review QT prolongation potential with newer nonselective serotonin reuptake
inhibitor (non-SSRI) antidepressants. Data Sources: A PubMed literature search was …

Antidepressant use and risk of out‐of‐hospital cardiac arrest: a nationwide case–time–control study

P Weeke, A Jensen, F Folke… - Clinical …, 2012 - Wiley Online Library
Treatment with some types of antidepressants has been associated with sudden cardiac
death. It is unknown whether the increased risk is due to a class effect or related to specific …