Plant derived active compounds of ayurvedic neurological formulation, Saraswatharishta as a potential dual leucine zipper kinase inhibitor: an in-silico study
Recent findings have highlighted the essential role of dual leucine zipper kinase (DLK) in
neuronal degeneration. Saraswatharishta (SWRT), an ayurvedic formulation utilized in …
neuronal degeneration. Saraswatharishta (SWRT), an ayurvedic formulation utilized in …
Prediction of Rab5B inhibitors through integrative in silico techniques
Rab5B is a small monomeric G protein that regulates early endocytosis and controls
signaling pathways related to cell growth, survival, and apoptosis. Dysregulation of Rab5B …
signaling pathways related to cell growth, survival, and apoptosis. Dysregulation of Rab5B …
Withania somnifera extract reduces gastric cancerous properties through inhibition of gankyrin in cellular milieu produced by Helicobacter pylori and Epstein Barr …
Abstract Helicobacter pylori and Epstein Barr virus (EBV) are group1 carcinogens and their
role in Gastric cancer (GC) is well established. Previously we have shown that H. pylori and …
role in Gastric cancer (GC) is well established. Previously we have shown that H. pylori and …
1, 7-Bis (4-hydroxyphenyl)-1, 4, 6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein
Y Liu, K Sa, W Xu, Y Chen, J Liang, P Zou… - Acta Materia …, 2023 - scienceopen.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread globally since
2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2 …
2020. The nucleocapsid (N) protein plays a crucial role in the life cycle of SARS-CoV-2 …
Computational insights into VacA toxin inhibition: harnessing FDA-approved antibiotics against Helicobacter pylori
Cancer is a condition in which a few of the body's cells grow beyond its control and spread
to other outward regions. Globally, gastric cancer (GC) is third most common cause of …
to other outward regions. Globally, gastric cancer (GC) is third most common cause of …
Multi-omics strategy reveals that Cordyceps sinensis ameliorates sepsis-associated acute kidney injury via reprogramming of mitochondrial energy metabolism and …
L Chen, T Yang, J Wu, G Cheng, M Zhao… - Acta Materia …, 2024 - scienceopen.com
Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …
medicine for the prevention, treatment, and prognostication of various diseases, because of …
In Silico Identification of a Potential TNF‐Alpha Binder Using a Structural Similarity: A Potential Drug Repurposing Approach to the Management of Alzheimer's …
EJ Tettevi, DNO Kuevi, BK Sumabe… - BioMed Research …, 2024 - Wiley Online Library
Introduction. Alzheimer's disease (AD) is a neurodegenerative disorder with no conclusive
remedy. Yohimbine, found in Rauwolfia vomitoria, may reduce brain inflammation by …
remedy. Yohimbine, found in Rauwolfia vomitoria, may reduce brain inflammation by …
[HTML][HTML] Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity
J Lu, Y Cheng, Y Zhang, Y Wang, B Xia, L Zhang… - Bioorganic & Medicinal …, 2024 - Elsevier
Here, we report the synthesis of a series of oxyacanthine derivatives and evaluation for their
anti-SARS-CoV-2 activity in Vero E6 cells. In order to eliminate the potential metabolic …
anti-SARS-CoV-2 activity in Vero E6 cells. In order to eliminate the potential metabolic …
Flavonoids: Inhibitors at Stages of Infection by SARS-CoV-2
JD Abidharini, A Pavithra, A Boro… - Anti-SARS-CoV-2 … - taylorfrancis.com
An RNA virus belonging to the Ortho Coronaviridae subfamily is the cause of the deadly
zoonotic respiratory disease well-known as Severe Acute Respiratory Syndrome (SARS). Its …
zoonotic respiratory disease well-known as Severe Acute Respiratory Syndrome (SARS). Its …