Genetic, molecular, and cellular determinants of sex-specific cardiovascular traits

F Vaura, J Palmu, J Aittokallio, A Kauko… - Circulation …, 2022 - Am Heart Assoc
Despite the well-known sex dimorphism in cardiovascular disease traits, the exact genetic,
molecular, and cellular underpinnings of these differences are not well understood. A …

A review of novel cardiac biomarkers in acute or chronic cardiovascular diseases: the role of soluble ST2 (sST2), lipoprotein‐associated phospholipase A2 (Lp‐PLA2) …

J Li, T Cao, Y Wei, N Zhang, Z Zhou, Z Wang… - Disease …, 2021 - Wiley Online Library
While the received traditional predictors are still the mainstay in the diagnosis and prognosis
of CVD events, increasing studies have focused on exploring the ancillary effect of …

High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies

HB Beyene, G Olshansky, AA T. Smith, C Giles… - PLoS …, 2020 - journals.plos.org
Obesity and related metabolic diseases show clear sex-related differences. The growing
burden of these diseases calls for better understanding of the age-and sex-related metabolic …

Combined high-density lipoprotein proteomic and glycomic profiles in patients at risk for coronary artery disease

S Krishnan, J Huang, H Lee, A Guerrero… - Journal of proteome …, 2015 - ACS Publications
Objectives: To test whether recently developed methods for comprehensive profiling of the
high-density lipoprotein (HDL) glycome combined with the HDL proteome can distinguish …

Interpretation of lipoprotein-associated phospholipase A2 levels is influenced by cardiac disease, comorbidities, extension of atherosclerosis and treatments

JC Charniot, R Khani-Bittar, JP Albertini, P Giral… - International journal of …, 2013 - Elsevier
Purpose Lipoprotein-associated phospholipase A2 (Lp-PLA2) is an inflammatory biomarker
secreted in the atherosclerotic plaque. Blood levels of Lp-PLA2 predict future cardiovascular …

Consumption of enriched yogurt with paf inhibitors from olive pomace affects the major enzymes of PAF metabolism: A randomized, double blind, three arm trial

M Detopoulou, A Ntzouvani, F Petsini, L Gavriil… - Biomolecules, 2021 - mdpi.com
Platelet-activating factor (PAF), a proinflammatory lipid mediator, plays a crucial role in the
formation of the atherosclerotic plaque. Therefore, the inhibition of endothelium inflammation …

Obesity and lifespan health—importance of the fetal environment

AF Tarantal, L Berglund - Nutrients, 2014 - mdpi.com
A marked increase in the frequency of obesity at the population level has resulted in an
increasing number of obese women entering pregnancy. The increasing realization of the …

The Use of lipoprotein-associated phospholipase A2 in a Chinese population to predict cardiovascular events

XI Hui, GL Cheng, FF Hu, SN Li, D Xuan… - Biomedical and …, 2022 - Elsevier
Objective To explore associations between lipoprotein-associated phospholipase A2 (Lp-
PLA2) and the risk of cardiovascular events in a Chinese population, with a long-term follow …

Variation of lipoprotein associated phospholipase A2 across demographic characteristics and cardiovascular risk factors: a systematic review of the literature

J Gregson, HA Stirnadel-Farrant, IU Doobaree, C Koro - Atherosclerosis, 2012 - Elsevier
BACKGROUND: Lipoprotein association phospholipase A2 (Lp-PLA2), an enzyme which
has been found in atherosclerotic plaque is currently under investigation in large Phase III …

Age as a modulator of inflammatory cardiovascular risk factors

E Anuurad, B Enkhmaa, Z Gungor… - … , and vascular biology, 2011 - Am Heart Assoc
Objective—Levels of acute phase reactants are affected by age. The extent to which
cardiovascular risk associated with aging is due to an increase in the inflammatory burden is …