Lacking conventional lymphatic system, the central nervous system requires alternative
clearance systems, such as the glymphatic system, which promotes clearance of interstitial …

Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …

Aquaporin channels facilitate bidirectional water flow in all cells and tissues. AQP4 is highly
expressed in astrocytes. In the CNS, it is enriched in astrocyte endfeet, at synapses, and at …

The aquaporins (AQPs) are a family of small integral membrane proteins that facilitate the
bidirectional transport of water across biological membranes in response to osmotic …

Vascular changes represent a characteristic feature of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) infection leading to a breakdown of the vascular barrier and …

In the last decade, research on acute respiratory distress syndrome (ARDS) has made
considerable progress. However, ARDS remains a leading cause of mortality in the …

Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide, and it
is the second leading cause of cancer-related mortality. Aquaporin 9 (AQP9) is an essential …

Alzheimer's disease (AD) is a neurodegenerative disease and the world's primary cause of
dementia, a condition characterized by significant progressive declines in memory and …

Sjögren's syndrome (SS) is a systemic autoimmune rheumatic disorder characterized by the
lymphocytic infiltration of exocrine glands and the production of autoantibodies to self …

Inflammasomes are large immune multiprotein complexes that tightly regulate the
production of the pro-inflammatory cytokines, being dependent on cell regulatory volume …