Incretins and microvascular complications of diabetes: neuropathy, nephropathy, retinopathy and microangiopathy

J Goldney, JA Sargeant, MJ Davies - Diabetologia, 2023 - Springer
Glucagon-like peptide-1 receptor agonists (GLP-1RAs, incretin mimetics) and dipeptidyl
peptidase-4 inhibitors (DPP-4is, incretin enhancers) are glucose-lowering therapies with …

SGLT-2 inhibitors and GLP-1 receptor agonists in metabolic dysfunction-associated fatty liver disease

JS Moon, JH Hong, YJ Jung, E Ferrannini… - Trends in Endocrinology …, 2022 - cell.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a chronic condition that
affects nearly one billion people globally, characterized by triacylglycerol accumulation in …

Anti-inflammatory properties of antidiabetic drugs: a “promised land” in the COVID-19 era?

N Katsiki, E Ferrannini - Journal of Diabetes and its Complications, 2020 - Elsevier
Inflammation is implicated in the development and severity of the coronavirus disease 2019
(COVID-19), as well as in the pathophysiology of diabetes. Diabetes, especially when …

[HTML][HTML] Targeting neuroinflammation in distal symmetrical polyneuropathy in diabetes

ZZ Chong, DL Menkes, N Souayah - Drug discovery today, 2024 - Elsevier
Diabetic distal symmetric polyneuropathy is the most common type of peripheral neuropathy
complication of diabetes mellitus. Neuroinflammation is emerging as an important …

How inflammation dictates diabetic peripheral neuropathy: An enlightening review

Y Cheng, Y Chen, K Li, S Liu, C Pang… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Diabetic peripheral neuropathy (DPN) constitutes a debilitating complication
associated with diabetes. Although, the past decade has seen rapid developments in …

How do SGLT2 (sodium-glucose cotransporter 2) inhibitors and GLP-1 (glucagon-like peptide-1) receptor agonists reduce cardiovascular outcomes? Completed and …

MMY Lee, MC Petrie, JJV McMurray… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: There is substantial interest in how GLP-1RA (glucagon-like peptide-1 receptor
agonists) and SGLT2 (sodium-glucose cotransporter 2) inhibitors reduce cardiovascular and …

Incretins beyond type 2 diabetes

C Mathieu, I Ahmadzai - Diabetologia, 2023 - Springer
Incretin-based therapies, in particular glucagon-like peptide-1 (GLP-1) receptor agonists,
have been evaluated in other forms of diabetes, but randomised controlled trials are mainly …

Effect of treatment with exenatide and pioglitazone or basal-bolus insulin on diabetic neuropathy: a substudy of the Qatar Study

G Ponirakis, MA Abdul-Ghani, A Jayyousi… - BMJ Open Diabetes …, 2020 - drc.bmj.com
Introduction To assess the effect of exenatide and pioglitazone or basal-bolus insulin on
diabetic peripheral neuropathy (DPN) in patients with poorly controlled type 2 diabetes …

Incretin-based therapies role in COVID-19 era: evolving insights

AP Stoian, N Papanas, M Prazny… - Journal of …, 2020 - journals.sagepub.com
The current coronavirus disease 2019 (COVID-19) pandemic has led the scientific
community to breach new frontiers in the understanding of human physiology and disease …

Glucagon-like peptide 1 analogues as adjunctive therapy for patients with type 1 diabetes: an updated systematic review and meta-analysis

J Park, S Ntelis, E Yunasan, KD Downton… - The Journal of …, 2024 - academic.oup.com
Context Concomitant obesity is common amongst patients with type 1 diabetes mellitus
(T1DM), yet adjunctive therapy options are scarce. Objective We assess the efficacy and …