The formation of high-affinity antibodies that protect against infection requires the formation
of germinal centres (GCs), where specialized T follicular helper cells (Tfh) provide help to B …

Cancer cells often overexpress CD47, which triggers the inhibitory receptor SIRPα
expressed on macrophages, to elude phagocytosis and antitumor immunity …

Macrophage-mediated programmed cell removal (PrCR) is crucial for the identification and
elimination of needless cells that maintain tissue homeostasis. The efficacy of PrCR …

The expansion of follicular helper T (Tfh) cells, which is tightly associated with the
development of lupus, is reversed by the inhibition of either glycolysis or glutaminolysis in …

Infection of mice by mouse cytomegalovirus (MCMV) triggers activation and expansion of
Ly49H+ natural killer (NK) cells, which are virus specific and considered to be" adaptive" or" …

Scrub typhus is a poorly studied but life-threatening disease caused by the intracellular
bacterium Orientia tsutsugamushi (Ot). Cellular and humoral immunity in Ot-infected patients …

Latent viral reservoirs (VRs) represent a main barrier to HIV cure. Thus, developing new
approaches that can purge and eliminate VRs paves the path toward achieving an HIV-1 …

T peripheral helper (Tph) cells are a newly discovered subtype of CD4+ T cells that have
emerged as the counterpart of T follicular helper (Tfh) cells in the peripheral tissues. These …

Germinal center (GC)-derived memory B cells (MBCs) play a pivotal role in humoral
immunity by differentiating into protective antibody-secreting cells upon re-infection. Despite …

Objective Signaling lymphocytic activation molecule family members (SLAMFs) play a
critical role in immune regulation of malignancies. This study aims to investigate the …