Natural product interventions for chemotherapy and radiotherapy-induced side effects

QY Zhang, FX Wang, KK Jia, LD Kong - Frontiers in pharmacology, 2018 - frontiersin.org
Cancer is the second leading cause of death in the world. Chemotherapy and radiotherapy
are the common cancer treatments. However, the development of adverse effects resulting …

Petroselinum crispum (Mill.) Fuss (Parsley): An Updated Review of the Traditional Uses, Phytochemistry, and Pharmacology

R Bahramsoltani, R Ahmadian, M Daglia… - Journal of Agricultural …, 2024 - ACS Publications
Petroselinum crispum (Mill.) Fuss (parsley) is a popular medicinal plant widely used in
different traditional medicines all over the world. This paper provides an updated review on …

Melatonin mitigates cisplatin-induced ovarian dysfunction via altering steroidogenesis, inflammation, apoptosis, oxidative stress, and PTEN/PI3K/Akt/mTOR/AMPK …

A Al-Shahat, MAE Hulail, NMM Soliman, T Khamis… - Pharmaceutics, 2022 - mdpi.com
Ovarian damage and fertility impairment are major side effects of chemotherapy in pre-
menopausal cancer patients. Cisplatin is a widely used chemotherapeutic drug. The present …

[HTML][HTML] Exploring the possible neuroprotective and antioxidant potency of lycopene against acrylamide-induced neurotoxicity in rats' brain

SM Farouk, FA Gad, R Almeer, MM Abdel-Daim… - Biomedicine & …, 2021 - Elsevier
Acrylamide (Ac) is a carbonyl compound extracted from hydrated acrylonitrile with a
significantly high chemical activity. It is widely existed and used in food processing, industrial …

The Protective Potential of Petroselinum crispum (Mill.) Fuss. on Paracetamol-Induced Hepatio-Renal Toxicity and Antiproteinuric Effect: A Biochemical …

G Nouioura, T Kettani, M Tourabi, LT Elousrouti… - Medicina, 2023 - mdpi.com
Background and Objectives: Paracetamol overdose is a significant global issue due to its
widespread use, which can lead to a lack of awareness regarding its potential side effects …

Protective effect of rutin supplementation against cisplatin-induced Nephrotoxicity in rats

AR Alhoshani, MM Hafez, S Husain, AM Al-Sheikh… - BMC nephrology, 2017 - Springer
Background Cisplatin (CP) is commonly used in the treatment of different types of cancer but
nephrotoxicity has been a major limiting factor. Therefore, the present study aimed to study …

Impact of garlic (Allium sativum) oil on cisplatin-induced hepatorenal biochemical and histopathological alterations in rats

MM Abdel-Daim, HG Abdel-Rahman… - Science of the total …, 2020 - Elsevier
Cisplatin (cis-diamminedichloridoplatinum II [CDDP]) is a chemotherapeutic agent used for
treating different cancers types. However, its usage is limited because it induces harmful …

Effect of parsley essential oil on digestive enzymes, intestinal morphometry, blood chemistry and stress-related genes in liver of Nile tilapia fish exposed to Bifenthrin

MR Farag, M Alagawany, SR Khalil, RM Abd El-Aziz… - Aquaculture, 2022 - Elsevier
Abstract Bifenthrin (BF), third-generation synthetic pyrethroids (SPs), is extensively used as
an insecticide for its higher killing activity, upgraded stability, and lower mammalians toxicity …

[PDF][PDF] Ameliorating effect of lycopene and N-acetylcysteine against cisplatin-induced cardiac injury in rats

A Elsayed, A Elkomy, M Alkafafy, R Elkammar, SE Fadl… - Pak Vet J, 2022 - researchgate.net
Cisplatin (CP) is used to treat a wide range of tumors and kills cells (anti-neoplastic drug)
through different mechanisms, including, formation of reactive oxygen species (ROS), DNA …

Pioglitazone ameliorates cisplatin-induced testicular toxicity by attenuating oxidative stress and inflammation via TLR4/MyD88/NF-κB signaling pathway

S Hussein, GAM Kamel - Journal of Trace Elements in Medicine and …, 2023 - Elsevier
Background Cisplatin (CIS) is a chemotherapeutic agent widely used to cure several
cancers. It exerts detrimental cellular effects that restrain its clinical application as an …