Approaches in Gene Coexpression Analysis in Eukaryotes

VL Zogopoulos, G Saxami, A Malatras… - Biology, 2022 - mdpi.com
Simple Summary Genes whose expression levels rise and fall similarly in a large set of
samples, may be considered coexpressed. Gene coexpression analysis refers to the en …

A knowledge graph approach to predict and interpret disease-causing gene interactions

A Renaux, C Terwagne, M Cochez, I Tiddi, A Nowé… - BMC …, 2023 - Springer
Background Understanding the impact of gene interactions on disease phenotypes is
increasingly recognised as a crucial aspect of genetic disease research. This trend is …

[HTML][HTML] Arabidopsis Coexpression Tool: a tool for gene coexpression analysis in Arabidopsis thaliana

VL Zogopoulos, G Saxami, A Malatras, A Angelopoulou… - Iscience, 2021 - cell.com
Gene coexpression analysis refers to the discovery of sets of genes which exhibit similar
expression patterns across multiple transcriptomic data sets, such as microarray experiment …

Novel targets in drug discovery

S Jankie, S Singh, N Laurieri, R Delgoda - Pharmacognosy, 2024 - Elsevier
Target discovery helps identify biomolecules or molecular interactions, which constitute
critical elements in the pathophysiological cellular pathway and are predicted to be …

[HTML][HTML] Gene coexpression analysis in Arabidopsis thaliana based on public microarray data

VL Zogopoulos, A Malatras, I Michalopoulos - STAR protocols, 2022 - Elsevier
Coexpressed genes tend to participate in related biological processes. Gene coexpression
analysis allows the discovery of functional gene partners or the assignment of biological …

A Cartographic Tool to Predict Disease Risk-associated Pseudo-Dynamic Networks from Tissue-specific Gene Expression

C Chen, B Shen, L Zhang, T Yu, M Wang, R Wu - Bio-protocol, 2023 - bio-protocol.org
Understanding how genes are differentially expressed across tissues is key to reveal the
etiology of human diseases. Genes are never expressed in isolation, but rather co …

Optimized Molecular Interaction Networks for the Study of Skeletal Muscle

S Morgan, A Malatras, S Duguez… - Journal of …, 2021 - content.iospress.com
Background: Molecular interaction networks (MINs) aim to capture the complex relationships
between interacting molecules within a biological system. MINs can be constructed from …