The success of platinum-based anticancer agents has motivated the exploration of novel
metal-based drugs for several decades, whereas problems such as drug-resistance and …

Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …

Photoactivated chemotherapy is an approach where a biologically active compound is
protected against interaction with the cell environment by a light-cleavable protecting group …

Hydrogels are commonly used as engineered extracellular matrix (ECM) mimics in
applications ranging from tissue engineering to in vitro disease models. Ideal mechanisms …

Polypyridyl coordinating ligands are common in metal complexes used in medicinal
inorganic chemistry. These ligands possess intrinsic cytotoxicity, but detailed data on this …

The clinical approval of platinum‐based drugs has prompted the development of novel
metallo‐complexes during the last several decades, while severe problems, especially for …

Photoactivated chemotherapy (PACT) is a novel cancer treatment method that has drawn
increasing attention due to its high selectivity and low side effects by spatio-temporal control …

The preparation of two new Ru (II)/diphosphine complexes containing Lapachol (Lap) and
Lawsone (Law):(1)[Ru (Lap)(dppm) 2] PF 6 and (2)[Ru (Law)(dppm) 2] PF 6, where dppm …

Ruthenium (II) polypyridyl complexes exhibit a lack of selectivity toward cancer tissues
despite extensive studies as photosensitizers for photodynamic therapy (PDT). Here, we …

Light-activated compounds are powerful tools and potential agents for medical applications,
as biological effects can be controlled in space and time. Ruthenium polypyridyl complexes …