Flavonoids in cancer and apoptosis

M Abotaleb, SM Samuel, E Varghese, S Varghese… - Cancers, 2018 - mdpi.com
Cancer is the second leading cause of death globally. Although, there are many different
approaches to cancer treatment, they are often painful due to adverse side effects and are …

Molecular mechanisms of action of genistein in cancer: Recent advances

HS Tuli, MJ Tuorkey, F Thakral, K Sak… - Frontiers in …, 2019 - frontiersin.org
Background: Genistein is one among the several other known isoflavones that is found in
different soybeans and soy products. The chemical name of genistein is 4′, 5, 7 …

Recent updates on anticancer mechanisms of polyphenols

E Sharma, DC Attri, P Sati, P Dhyani… - Frontiers in Cell and …, 2022 - frontiersin.org
In today's scenario, when cancer cases are increasing rapidly, anticancer herbal
compounds become imperative. Studies on the molecular mechanisms of action of …

Chemical structure, sources and role of bioactive flavonoids in cancer prevention: a review

G Drețcanu, I Știrbu, N Leoplold, D Cruceriu… - Plants, 2022 - mdpi.com
There has been a major shift in the collective mindset around the world in recent decades,
both in terms of food and in terms of the treatment of chronic diseases. Increasing numbers …

Genistein induces apoptosis in vitro and has antitumor activity against human leukemia HL‐60 cancer cell xenograft growth in vivo

YC Hsiao, SF Peng, KC Lai, CL Liao… - Environmental …, 2019 - Wiley Online Library
Genistein, a major isoflavone compound in soybeans, has been shown to have biological
activities including anti‐cancer activates. In the present, we investigated the anti‐leukemia …

Anticancer perspectives of genistein: a comprehensive review

H Naeem, U Momal, M Imran, M Shahbaz… - … Journal of Food …, 2023 - Taylor & Francis
There is a significant load of degenerative and chronic illnesses, especially cancer, which is
one of the main reasons for morbidity and death globally. Polyphenolic phytochemicals …

[HTML][HTML] Toxicity of saffron extracts on cancer and normal cells: A review article

M Shakeri, AH Tayer, H Shakeri… - Asian Pacific journal …, 2020 - ncbi.nlm.nih.gov
Methods: This review aims to provide an overview of in-vitro and in-vivo evaluation molecule
mechanism for anti-tumor activity, cancer preventing and protective effects of saffron extract …

[HTML][HTML] Peroxisome proliferator-activated receptor gamma as a therapeutic target for hepatocellular carcinoma: Experimental and clinical scenarios

S Katoch, V Sharma, V Patial - World Journal of Gastroenterology, 2022 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of liver cancer worldwide. Viral
hepatitis is a significant risk factor for HCC, although metabolic syndrome and diabetes are …

Roles of therapeutic bioactive compounds in hepatocellular carcinoma

D Jain, Y Murti, WU Khan, R Hossain… - Oxidative Medicine …, 2021 - Wiley Online Library
Hepatocellular carcinoma (HCC) is due to poor prognosis and lack of availability of effective
treatment. Novel therapeutic strategies will be the fine tuning of intracellular ROS signaling …

Differential apoptotic effects of bee product mixtures on normal and cancer hepatic cells

V Sánchez-Martín, P Morales, A Iriondo-DeHond… - Antioxidants, 2023 - mdpi.com
Most effective anticancer drugs normally generate considerable cytotoxicity in normal cells;
therefore, the preferential activation of apoptosis in cancer cells and the reduction of toxicity …