Background Faecal incontinence (FI) and constipation are both socially‐embarrassing and
physically‐disabling conditions that impair quality of life. For both, surgery may be required …

Background Sacral nerve stimulation (SNS) is now well established as a treatment for fecal
incontinence (FI) resistant to conservative measures and may also have utility in the …

Background Until recently, investigations of the normal patterns of motility of the healthy
human colon have been limited by the resolution of in vivo recording techniques. Methods …

Gastroenterologists frequently encounter pelvic floor disorders, which affect 10% to 15% of
the population. The anorectum is a complex organ that collaborates with the pelvic floor …

Postoperative ileus (POI) is an abnormal pattern of gastrointestinal motility characterized by
nausea, vomiting, abdominal distension and/or delayed passage of flatus or stool, which …

In recent years there have been significant technical and methodological advances in our
ability to record the movements of the gastrointestinal tract. This has led to significant …

Objectives: Sacral nerve stimulation (SNS) is a potential treatment for constipation refractory
to standard therapies. However, there have been no randomized controlled studies …

Background Slow transit constipation (STC) is associated with colonic motor abnormalities.
The underlying cause (s) of the abnormalities remain poorly defined. In health, utilizing high …

Background Sacral nerve stimulation (SNS) is an effective treatment for neurogenic faecal
incontinence (FI). However, the clinical improvement that patients experience cannot be …

Physical delivery of anticancer drugs in controlled anatomic locations can complement the
advances being made in chemo‐selective therapies. To this end, an optical fiber catheter is …