Acute upper gastrointestinal bleeding is an important emergency situation. Population-
based epidemiology data are important to get insight in the actual healthcare problem …

Nonsteroidal anti-inflammatory drugs (NSAIDs) are probably the most common cause of
gastroduodenal injury in the United States today. Approximately half of patients who …

Background The relation between H pylori infection and use of non-steroidal anti-
inflammatory drugs (NSAIDs) in the pathogenesis of peptic-ulcer disease is controversial …

By inhibiting prostaglandin synthesis, nonsteroidal anti-inflammatory drugs (NSAIDs)
compromise gastroduodenal defense mechanism including blood flow and …

Background & Aims: The aim was to systematically review the interactions between
Helicobacter pylori (HP) infection and NSAID use on the risk of uncomplicated or bleeding …

Objective: Research on ulcer psychosomatics has plummeted since the early 1970s, to the
applause of many who argue that ulcer is simply an infectious disease. The purpose of this …

Abstract Objective Studies in Western populations have shown the association of
nonsteroidal anti-inflammatory drugs (NSAIDs) and upper gastrointestinal bleeding (UGIB) …

Aim: To investigate the role of Helicobacter pylori, expressing the virulence marker CAGA
(cytotoxin associated gene product A) in ulcer complications and its interaction with …

OBJECTIVES: It has been suggested that prevalence ofHelicobacter pylori (Hp) in peptic
ulcer bleeding (PUB) is lower than that in non-complicated ulcers. AsHpinfection is elusive …

Background: There is controversy as to whether Helicobacter pylori and non‐steroidal anti‐
inflammatory drugs interact to cause peptic ulcers. Aim: To study whether the eradication of …