Advances in the treatment of neuromyelitis optica spectrum disorder

AI Wallach, M Tremblay, I Kister - Neurologic Clinics, 2021 - neurologic.theclinics.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare, relapsing-remitting
neuroinflammatory disorder of the central nervous system (CNS) usually associated with …

Neuromyelitis optica spectrum disorders (NMOSD) and connective tissue disease (CTD): an update for the rheumatologist

RA Cruz, S Chaudhary, M Guevara… - Current rheumatology …, 2021 - Springer
Abstract Purpose of Review To review the pathophysiology, presentation, and treatment of
neuromyelitis optica spectrum disorder (NMOSD) and its association with systemic lupus …

A two-way interaction between methotrexate and the gut microbiota of male sprague–dawley rats

MPM Letertre, N Munjoma, K Wolfer… - Journal of proteome …, 2020 - ACS Publications
Methotrexate (MTX) is a chemotherapeutic agent that can cause a range of toxic side effects
including gastrointestinal damage, hepatotoxicity, myelosuppression, and nephrotoxicity …

[HTML][HTML] Part II. High-dose methotrexate with leucovorin rescue for severe COVID-19: an immune stabilization strategy for SARS-CoV-2 induced 'PANIC'attack

EM Frohman, NR Villemarette-Pittman, RA Cruz… - Journal of the …, 2020 - Elsevier
Here, in Part II of a duology on the characterization and potential treatment for COVID-19, we
characterize the application of an innovative treatment regimen for the prevention of the …

[HTML][HTML] Ameliorating effects of tempol on methotrexate-induced liver injury in rats

N Pınar, M Kaplan, T Özgür, O Özcan - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Methotrexate (MTX) is used in the treatment of certain types of cancers and chronic
inflammatory illnesses, although the clinical use of MTX is limited due to its adverse effects …

Leucovorin ameliorated methotrexate induced intestinal toxicity via modulation of the gut microbiota

X Huang, Q Fang, T Rao, L Zhou, X Zeng, Z Tan… - Toxicology and applied …, 2020 - Elsevier
Methotrexate (MTX) is a widely used therapeutic agent for the treatment of cancer and
autoimmune diseases. However, its efficacy is often limited by adverse effects, such as …

[HTML][HTML] Part I. SARS-CoV-2 triggered 'PANIC'attack in severe COVID-19

EM Frohman, NR Villemarette-Pittman… - Journal of the …, 2020 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has produced a world-wide
collapse of social and economic infrastructure, as well as constrained our freedom of …

The first case report of preschool-onset SS/SLE coexisting with NMOSD of Chinese origin

L Liu, L Tang, L Zhang, X Li, P Huang, J Xiong… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is an autoimmune connective tissue disease (CTD),
the main features of which are multiple serum autoantibodies and extensive involvement of …

B cells and antibodies as targets of therapeutic intervention in neuromyelitis optica spectrum disorders

J Traub, L Husseini, MS Weber - Pharmaceuticals, 2021 - mdpi.com
The first description of neuromyelitis optica by Eugène Devic and Fernand Gault dates back
to the 19th century, but only the discovery of aquaporin-4 autoantibodies in a major subset of …

Clinical features and high-risk indicators of central nervous system involvement in primary Sjögren's syndrome

W Fan, J Par-Young, K Li, Y Zhang, P Xiao, L Hua… - Clinical …, 2023 - Springer
Background Evidence for central nervous system involvement in primary Sjögren's
syndrome (pSS) patients is controversial and extremely limited. We aimed to describe the …