[HTML][HTML] Belantamab mafodotin in multiple myeloma

EA Martino, A Bruzzese, E Iaccino… - Expert Opinion on …, 2023 - Taylor & Francis
The therapeutic scenario for multiple myeloma (MM) has changed drastically in recent years
with the introduction of new molecules, which lead to a more precise medicine, improving …

[HTML][HTML] Tumor-associated macrophages in multiple myeloma: key role in disease biology and potential therapeutic implications

E Cencini, A Sicuranza, S Ciofini, A Fabbri, M Bocchia… - Current …, 2023 - mdpi.com
Multiple myeloma (MM) is characterized by multiple relapse and, despite the introduction of
novel therapies, the disease becomes ultimately drug-resistant. The tumor …

Therapeutic potentials of adoptive cell therapy in immune-mediated neuropathy

S Shang, C Zhao, J Lin, D Cornblath, P van Doorn… - Journal of …, 2024 - Elsevier
Immune-mediated neuropathy (IMN) is a group of heterogenous neuropathies caused by
intricate autoimmune responses. For now, known mechanisms of different IMN subtypes …

[HTML][HTML] Safety of subcutaneous daratumumab in anti-CD38 monoclonal antibody-naive patients with plasma cell disorders: a multicenter real-life experience

D De Novellis, R Fontana, S Palmieri, R Della Pepa… - Targeted Oncology, 2023 - Springer
Background Daratumumab, an anti-CD38 monoclonal antibody, is used for treatment of
multiple myeloma (MM) and light chain amyloidosis at an intravenous dosage of 16 mg/kg or …

Cytomegalovirus reactivation is frequent in multiple myeloma patients treated with daratumumab‐based regimens

D De Novellis, R Fontana, B Serio, E Vaccaro… - Cancer …, 2024 - Wiley Online Library
Background Viral reactivations are frequent in hematologial patients due to their cancer‐
related and drug‐induced immunosuppressive status. Daratumumab, an anti‐CD38 …

Clinical Efficacy of Isatuximab Plus Carfilzomib and Dexamethasone in Relapsed/Refractory Multiple Myeloma Patients

D De Novellis, D Derudas, D Vincelli… - European Journal of …, 2024 - Wiley Online Library
Isatuximab, a novel anti‐CD38 monoclonal antibody, is approved in combination with
carfilzomib and dexamethasone (Isa‐Kd) in relapsed/refractory multiple myeloma (RRMM) …

[HTML][HTML] Macrophages and Urokinase Plasminogen Activator Receptor System in Multiple Myeloma: Case Series and Literature Review

P Manzo, V Giudice, F Napolitano… - International Journal of …, 2023 - mdpi.com
The microenvironment plays an essential role in multiple myeloma (MM) development,
progression, cell proliferation, survival, immunological escape, and drug resistance …

Current progress in chimeric antigen receptor T‐cell therapy for malignant tumors

Y Zheng, J Huang, Y Xu, HY Luo - MedComm–Future Medicine, 2024 - Wiley Online Library
In the realm of malignant tumor treatment, particularly regarding hematologic malignancies,
chimeric antigen receptor T‐cell (CAR‐T) immunotherapy has witnessed remarkable …

[HTML][HTML] Diagnosis of light‑chain deposition disease after renal transplantation: A case report and literature review

J Yue, F Xu, Y Zhang, J Wen… - Experimental and …, 2024 - spandidos-publications.com
Light chain deposition disease (LCDD) is a rare, clonal plasma cell proliferative condition.
The deposition of nonamyloid monoclonal immunoglobulin light chains predominantly …

Efficacy and safety of teclistamab in patients with relapsed/refractory multiple myeloma after BCMA-targeting therapies

C Touzeau, AY Krishnan, P Moreau, A Perrot… - Blood …, 2024 - ashpublications.org
Teclistamab is a B‑cell maturation antigen (BCMA)-directed bispecific antibody approved for
the treatment of patients with triple-class exposed relapsed/refractory multiple myeloma. In …