Metabolic channeling: predictions, deductions, and evidence
With the elucidation of myriad anabolic and catabolic enzyme-catalyzed cellular pathways
crisscrossing each other, an obvious question arose: how could these networks operate with …
crisscrossing each other, an obvious question arose: how could these networks operate with …
In Silico Identification and Experimental Validation of Distal Activity-Enhancing Mutations in Tryptophan Synthase
MA Maria-Solano, T Kinateder… - ACS …, 2021 - ACS Publications
Allostery is a central mechanism for the regulation of multi-enzyme complexes. The
mechanistic basis that drives allosteric regulation is poorly understood but harbors key …
mechanistic basis that drives allosteric regulation is poorly understood but harbors key …
Production of indole by Corynebacterium glutamicum microbial cell factories for flavor and fragrance applications
M Mindt, A Beyraghdar Kashkooli, M Suarez-Diez… - Microbial Cell …, 2022 - Springer
Background The nitrogen containing aromatic compound indole is known for its floral odor
typical of jasmine blossoms. Due to its characteristic scent, it is frequently used in dairy …
typical of jasmine blossoms. Due to its characteristic scent, it is frequently used in dairy …
Toward an evaluation of metabolite channeling in vivo
T Obata - Current opinion in biotechnology, 2020 - Elsevier
Highlights•Intermediate metabolites are channeled between metabolic pathway
enzymes.•Metabolite channeling is a promising tool to regulate metabolic pathway …
enzymes.•Metabolite channeling is a promising tool to regulate metabolic pathway …
Analysis of allosteric communication in a multienzyme complex by ancestral sequence reconstruction
M Schupfner, K Straub, F Busch… - Proceedings of the …, 2020 - National Acad Sciences
Tryptophan synthase (TS) is a heterotetrameric αββα complex. It is characterized by the
channeling of the reaction intermediate indole and the mutual activation of the α-subunit …
channeling of the reaction intermediate indole and the mutual activation of the α-subunit …
Expanding the toolbox for functional genomics in Fonsecaea pedrosoi: The use of split-marker and biolistic transformation for inactivation of tryptophan synthase (trpB) …
LD Favilla, TS Herman, CS Goersch, RV de Andrade… - Journal of Fungi, 2023 - mdpi.com
Chromoblastomycosis (CBM) is a disease caused by several dematiaceous fungi from
different genera, and Fonsecaea is the most common which has been clinically isolated …
different genera, and Fonsecaea is the most common which has been clinically isolated …
Expandindo o estudo genético de Fonsecaea pedrosoi: o uso de marcadores e transformação biobalística para inativação do gene de triptofano sintase (trpB)
LD Favilla - 2024 - icts.unb.br
A cromoblastomicose (CBM) é uma doença causada por vários fungos demáceos de
diferentes gêneros, sendo que Fonsecaea o mais comum isolado clinicamente. Métodos de …
diferentes gêneros, sendo que Fonsecaea o mais comum isolado clinicamente. Métodos de …
Rational prediction of distal activity-enhancing mutations in tryptophan synthase
MÁN Maria-Solano, T Kinateder, J Iglesias-Fernández… - 2021 - chemrxiv.org
Allostery is a central mechanism for the regulation of multi-enzyme complexes. The
mechanistic basis that drives allosteric regulation is poorly understood, but harbors key …
mechanistic basis that drives allosteric regulation is poorly understood, but harbors key …