[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review

KA Thayer, JJ Heindel, JR Bucher… - Environmental health …, 2012 - ehp.niehs.nih.gov
Background: There has been increasing interest in the concept that exposures to
environmental chemicals may be contributing factors to the epidemics of diabetes and …

[HTML][HTML] Redox toxicology of environmental chemicals causing oxidative stress

F Zheng, FM Gonçalves, Y Abiko, H Li, Y Kumagai… - Redox biology, 2020 - Elsevier
Living organisms are surrounded with heavy metals such as methylmercury, manganese,
cobalt, cadmium, arsenic, as well as pesticides such as deltamethrin and paraquat, or …

Evaluation of the association between arsenic and diabetes: a National Toxicology Program workshop review

EA Maull, H Ahsan, J Edwards… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Diabetes affects an estimated 346 million persons globally, and total deaths
from diabetes are projected to increase> 50% in the next decade. Understanding the role of …

Health effects inflicted by chronic low‐level arsenic contamination in groundwater: A global public health challenge

D Sinha, P Prasad - Journal of Applied Toxicology, 2020 - Wiley Online Library
Groundwater arsenic (As) contamination is a global public health concern. The high level of
As exposure (100‐1000 μg/L or even higher) through groundwater has been frequently …

Environmental pollutants and type 2 diabetes: a review of mechanisms that can disrupt beta cell function

TLM Hectors, C Vanparys, K Van Der Ven, GA Martens… - Diabetologia, 2011 - Springer
The prevalence of diabetes mellitus is currently at epidemic proportions and it is estimated
that it will increase even further over the next decades. Although genetic predisposition and …

Environmental toxicants: human exposures and their health effects

M Lippmann - 2000 - books.google.com
A comprehensive guide to assessing the health effects of environmental toxicants in
nonoccupational settings Now in a second edition, Environmental Toxicants: Human …

Perspectives in endocrine toxicity of heavy metals—a review

SVS Rana - Biological trace element research, 2014 - Springer
An attempt has been made to review the endocrine/hormonal implications of a few
environmentally significant metals, viz, lead, mercury, cadmium, copper, arsenic and nickel …

Role of reactive oxygen species in glucose metabolism disorder in diabetic pancreatic β-cells

E Mukai, S Fujimoto, N Inagaki - Biomolecules, 2022 - mdpi.com
The dysfunction of pancreatic β-cells plays a central role in the onset and progression of
type 2 diabetes mellitus (T2DM). Insulin secretory defects in β-cells are characterized by a …

Association of low-moderate arsenic exposure and arsenic metabolism with incident diabetes and insulin resistance in the Strong Heart Family Study

M Grau-Perez, CC Kuo, MO Gribble… - Environmental …, 2017 - ehp.niehs.nih.gov
Background: High arsenic exposure has been related to diabetes, but at low-moderate
levels the evidence is mixed. Arsenic metabolism, which is partly genetically controlled and …