Demonstrations that grip strength has predictive power in relation to a range of health
conditions—even when these are assessed decades later—has motivated claims that hand …

Purpose: Loss of grip strength and cognitive impairment are prevalent in the elderly, and
they may share the pathogenesis in common. Several original studies have investigated the …

Cognitive decline in older adults contributes to reduced ability to perform daily tasks and
continued disuse leads to muscle weakness and potentiates functional loss. Despite explicit …

Introduction Cognitive impairment is the hallmark of Alzheimer's disease (AD) and related
dementias. However, motor decline has been recently described as a prodromal state that …

Dementia is characterized by a long preclinical phase that may last years to decades before
the onset of mild cognitive impairment. Slow gait speed and subjective memory complaint …

Objective Emerging evidence suggests that handgrip strength (a proxy for muscular fitness)
is associated with better cognitive performance in people with major depressive disorder …

Handgrip strength (HGS), a measure of muscular strength, might be a risk indicator for
cognitive functioning, but the evidence is not consistent. Using a new prospective study and …

Background Grip strength is an indicator of physical function with potential predictive value
for health in ageing populations. We assessed whether trends in grip strength from midlife …

Introduction To determine whether slowed gait and weakened grip strength independently,
or together, better identify risk of cognitive decline or dementia. Methods Time to walk 3 …

The cognitive reserve (CR) hypothesis is reinforced by negative moderating effects,
suggesting that those with higher CR are less reliant on brain structure for cognitive function …