Implications of the hybrid epithelial/mesenchymal phenotype in metastasis

MK Jolly, M Boareto, B Huang, D Jia, M Lu… - Frontiers in …, 2015 - frontiersin.org
Transitions between epithelial and mesenchymal phenotypes–the epithelial to
mesenchymal transition (EMT) and its reverse the mesenchymal to epithelial transition …

EMT: 2016

MA Nieto, RYJ Huang, RA Jackson, JP Thiery - cell, 2016 - cell.com
The significant parallels between cell plasticity during embryonic development and
carcinoma progression have helped us understand the importance of the epithelial …

In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition

JA Mitchel, A Das, MJ O'Sullivan, IT Stancil… - Nature …, 2020 - nature.com
The epithelial-to-mesenchymal transition (EMT) and the unjamming transition (UJT) each
comprises a gateway to cellular migration, plasticity and remodeling, but the extent to which …

[HTML][HTML] Stability of the hybrid epithelial/mesenchymal phenotype

MK Jolly, SC Tripathi, D Jia, SM Mooney, M Celiktas… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Abstract Epithelial-to-Mesenchymal Transition (EMT) and its reverse–Mesenchymal to
Epithelial Transition (MET)–are hallmarks of cellular plasticity during embryonic …

Cancer stem cells: A brief review of the current status

A Kuşoğlu, ÇB Avcı - Gene, 2019 - Elsevier
Cancer stem cells (CSCs) comprise the subpopulation of tumor bulk and acquire resistant to
conventional therapies and are considered as the primary tumor initiator cells. Nowadays …

MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination

M Lu, MK Jolly, H Levine… - Proceedings of the …, 2013 - National Acad Sciences
Forward and backward transitions between epithelial and mesenchymal phenotypes play
crucial roles in embryonic development and tissue repair. Aberrantly regulated transitions …

Fibroblast growth factor 2 accelerates the epithelial–mesenchymal transition in keratinocytes during wound healing process

Y Koike, M Yozaki, A Utani, H Murota - Scientific reports, 2020 - nature.com
In the wound healing process, the morphology of keratinocytes at the wound edge
temporarily changes to a spindle morphology, which is thought to occur due to an epithelial …

Epithelial–mesenchymal transition in lung development and disease: does it exist and is it important?

D Bartis, N Mise, RY Mahida, O Eickelberg, DR Thickett - Thorax, 2014 - thorax.bmj.com
Epithelial–mesenchymal transition (EMT) is a process when epithelial cells gradually
transform into mesenchymal-like cells losing their epithelial functionality and characteristics …

Inflammation: A key process in skin tumorigenesis

M Neagu, C Constantin, C Caruntu… - Oncology …, 2019 - spandidos-publications.com
The extremely delicate shift from an inflammatory process to tumorigenesis is a field of major
scientific interest. While the inflammation induced by environmental agents has well known …

Molecular mechanisms and treatment of radiation-induced lung fibrosis

NH Ding, J Jian Li, LQ Sun - Current drug targets, 2013 - ingentaconnect.com
Radiation-induced lung fibrosis (RILF) is a severe side effect of radiotherapy in lung cancer
patients that presents as a progressive pulmonary injury combined with chronic …