DNA origami nanoframes with two parallel DNA sequences are used to evaluate the effect of
nucleoside substituents on radiation-induced DNA damage. Double strand breaks (DSB) of …

Hypoxia, a hallmark of solid tumors, which account for ca. 80% of cancer cases, makes the
cancer cells resistant toward ionizing radiation and as a consequence to radiotherapy, one …

Reactive open-shell ring systems comprising C, N, O, and S atoms are crucial for the
radiation-induced molecular evolution and relevant to life and interstellar regions. Herein …

Substitution of exocyclic oxygen with sulfur was shown to substantially influence the
properties of RNA/DNA bases, which are crucial for prebiotic chemistry and photodynamic …

Molecular insight into electronic rearrangements and structural trajectories arising from
oxidative damages to DNA backbone is of crucial importance in understanding the effect of …

Simple Summary One of the most common diseases in the world is cancer. The
development of an appropriate treatment pathway for cancer patients seems to be crucial to …

Using molecular dynamics (MD) simulation, we simulate the structural change of a telomeric
DNA by β-decay of substituted tritium to helium-3. The configuration of the telomeric DNA is …

Telomeres are complex nucleoprotein assemblies that play a vital role in the maintenance of
functional ends of linear chromosomes. Telomeric DNA, composed of tandem repeats of the …