Computational vaccinology includes epitope mapping, antigen selection, and immunogen
design using computational tools. Tools that facilitate the in silico prediction of immune …

Next-generation vaccines that utilize T cells could potentially overcome the limitations of
current influenza vaccines that rely on antibodies to provide narrow subtype-specific …

A new strain of Influenza A Virus (IAV), so-called" H7N9 Avian Influenza", is the first strain of
this virus in which a human is infected by transmitting the N9 of influenza virus. Although …

Introduction The field of cancer therapy has undergone a major transformation in less than a
decade due to the introduction of checkpoint inhibitors, the advent of next generation …

Computational vaccine design, also known as computational vaccinology, encompasses
epitope mapping, antigen selection and immunogen design using computational tools. The …

Peptide drugs play an important part in medicine owing to their many therapeutic
applications. Of the 80 peptide drugs approved for use in humans, at least five are now off …

Zika virus (ZIKV) is a flavivirus primarily transmitted by Aedes species mosquitoes, first
discovered in Africa in 1947, that disseminated through Southeast Asia and the Pacific …

Introduction Clinical trials of personalized cancer vaccines have shown that on-demand
therapies that are manufactured for each patient, result in activated T cell responses against …

In silico immunogenicity risk assessment has been an important step in the development
path for many biologic therapeutics, including monoclonal antibodies. Even if the source of a …

Influenza world-wide causes significant morbidity and mortality annually, and more severe
pandemics when novel strains evolve to which humans are immunologically naïve. Because …