Neurotransmitters are special molecules that serve as messengers in chemical synapses
between neurons, cells, or receptors, including catecholamines, serotonin, dopamine, and …

Activation of hepatocyte cannabinoid receptor-1 (CB 1 R) by hepatic stellate cell (HSC)-
derived 2-arachidonoylglycerol (2-AG) drives de novo lipogenesis in alcoholic liver disease …

Background and Aims The important roles of glutamate and metabotropic glutamate
receptor 5 (mGluR5) in HSCs have recently been reported in various liver diseases; …

Introduction Brain death (BD) and steatosis are both risk factors for organ dysfunction or
failure in liver transplantation (LT) Material and methods Here, we examine the role of …

The endogenous antioxidant defense plays a big part in the pathogenesis of non-alcoholic
fatty liver disease (NAFLD), a common metabolic disorder that can lead to serious …

Ischemia-reperfusion injury (IRI) is a major cause of graft loss and dysfunction in clinical
transplantation and organ resection. The predominant focus on immunological rejection in …

The metabotropic glutamate receptor 5 (mGluR5) is an essential modulator of synaptic
plasticity, learning and memory; whereas in pathological conditions, it is an acknowledged …

It has been previously found that the blockade of metabotropic glutamate receptor type 5
(mGluR5) protects against hepatic ischemia/reperfusion injury and acetaminophen toxicity …

The blockade of metabotropic glutamate receptor type 5 (mGluR5) was previously found to
reduce fat accumulation in HEPG2 cells. Here, we evaluated the effects of mGluR5 blockade …

We previously demonstrated that the blockade of mGluR5 by 2-methyl-6 (phenylethynyl)
pyridine (MPEP) reduces both cold and warm ischemia/reperfusion injury. Here we …