Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

Complex regional pain syndrome is a chronic pain condition characterized by autonomic
and inflammatory features. It occurs acutely in about 7% of patients who have limb fractures …

Neuropathic pain (NP) is often refractory to pharmacologic and noninterventional treatment.
On behalf of the International Association for the Study of Pain Neuropathic Pain Special …

Pain is a common problem in cancer survivors, especially in the first few years after
treatment. In the longer term, approximately 5% to 10% of survivors have chronic severe …

The transition from acute to chronic pain states might be the most important challenge in
research to improve clinical treatment of debilitating pain. We describe a recently identified …

Background There is currently no strong consensus regarding the optimal management of
complex regional pain syndrome although a multitude of interventions have been described …

It is from the discovery of leptin and the central nervous system as a regulator of bone
remodeling that the presence of autonomic nerves within the skeleton transitioned from a …

Complex regional pain syndrome (CRPS) is a term used to describe a variety of disorders
characterized by spontaneous or stimulus-induced pain that is disproportional to the inciting …

Background This is an updated version of the original Cochrane review published in Issue 3,
2006, which included 23 trials. The use of opioids for neuropathic pain remains …

BACKGROUND: IV ketamine is widely used to treat patients with chronic pain, yet the long-
term impact remains uncertain. We synthesized evidence from randomized control trials to …