Chronic inflammation and cytokines in the tumor microenvironment

G Landskron, M De la Fuente… - Journal of …, 2014 - Wiley Online Library
Acute inflammation is a response to an alteration induced by a pathogen or a physical or
chemical insult, which functions to eliminate the source of the damage and restore …

Treatment algorithm for mild and moderate-to-severe ulcerative colitis: an update

E Burri, MH Maillard, AM Schoepfer, F Seibold… - Digestion, 2020 - karger.com
Background: Patient care in ulcerative colitis (UC) remains challenging despite an array of
established treatment options and emerging new therapies. The management of UC therapy …

The association of tissue anti-TNF drug levels with serological and endoscopic disease activity in inflammatory bowel disease: the ATLAS study

AJ Yarur, A Jain, DA Sussman, JS Barkin, MA Quintero… - Gut, 2016 - gut.bmj.com
Objective The aim of this study was to assess the correlation between serum and intestinal
anti-tumour necrosis factor (TNF) levels, and their relationship to endoscopic disease activity …

[HTML][HTML] Sleep, immunity and inflammation in gastrointestinal disorders

T Ali, J Choe, A Awab, TL Wagener… - World journal of …, 2013 - ncbi.nlm.nih.gov
Sleep disorders have become a global issue, and discovering their causes and
consequences are the focus of many research endeavors. An estimated 70 million …

local tumor necrosis factor-α inhibition in inflammatory bowel disease

B Gareb, AT Otten, HW Frijlink, G Dijkstra… - Pharmaceutics, 2020 - mdpi.com
Crohn's disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBD)
characterized by intestinal inflammation. Increased intestinal levels of the proinflammatory …

[HTML][HTML] Inflammatory bowel disease-associated interleukin-33 is preferentially expressed in ulceration-associated myofibroblasts

J Sponheim, J Pollheimer, T Olsen, J Balogh… - The American journal of …, 2010 - Elsevier
Interleukin-33 (IL-33) is a novel member of the interleukin-1 family that induces mucosal
pathology in vivo and may drive fibrosis development and angiogenesis. To address its …

Computer-aided imaging analysis of probe-based confocal laser endomicroscopy with molecular labeling and gene expression identifies markers of response to …

M Iacucci, L Jeffery, A Acharjee, E Grisan… - Inflammatory Bowel …, 2023 - academic.oup.com
Background We aimed to predict response to biologics in inflammatory bowel disease (IBD)
using computerized image analysis of probe confocal laser endomicroscopy (pCLE) in vivo …

Rescue therapies for steroid-refractory acute severe ulcerative colitis: a review

JP Gisbert, MJ García… - Journal of Crohn's and …, 2023 - academic.oup.com
Background One-third of patients with acute severe ulcerative colitis [ASUC] are steroid-
refractory. We aimed to review the different options for the management of steroid-refractory …

the practical management of acute severe ulcerative colitis

D Seah, P De Cruz - Alimentary pharmacology & therapeutics, 2016 - Wiley Online Library
Background Acute severe ulcerative colitis (ASUC) is a life‐threatening condition for which
optimal management strategies remain ill‐defined. Aim To review the evidence regarding …

TH1 and TH17 interactions in untreated inflamed mucosa of inflammatory bowel disease, and their potential to mediate the inflammation

T Olsen, R Rismo, G Cui, R Goll, I Christiansen… - Cytokine, 2011 - Elsevier
BACKGROUND: Crohn's disease (CD) and ulcerative colitis (UC) have been associated
with a T helper1 (TH1) and a TH2 cytokine profile, respectively. Recently, a TH17 lineage …