Human ectopic olfactory receptors and their food originated ligands: A review

RN Raka, H Wu, J Xiao, I Hossen, Y Cao… - Critical Reviews in …, 2022 - Taylor & Francis
Ectopic olfactory receptors (EORs) are expressed in non-nasal tissues of human body. They
belong to the G-protein coupled receptor (GPCR) superfamily. EORs may not be capable of …

Metabolic activity organizes olfactory representations

WW Qian, JN Wei, B Sanchez-Lengeling, BK Lee… - Elife, 2023 - elifesciences.org
Hearing and vision sensory systems are tuned to the natural statistics of acoustic and
electromagnetic energy on earth and are evolved to be sensitive in ethologically relevant …

General Chemical Reaction Network Theory for Olfactory Sensing Based on G-Protein-Coupled Receptors: Elucidation of Odorant Mixture Effects and Agonist …

WK Kim, K Choi, C Hyeon, SJ Jang - The Journal of Physical …, 2023 - ACS Publications
This work presents a general chemical reaction network theory for olfactory sensing
processes that employ G-protein-coupled receptors as olfactory receptors (ORs). The theory …

Water-mediated biomolecular dynamics and allostery

DM Leitner, C Hyeon, KM Reid - The Journal of Chemical Physics, 2020 - pubs.aip.org
Dynamic coupling with water contributes to regulating the functional dynamics of a
biomolecule. We discuss protein–water dynamics, with emphasis on water that is partially …

Olfactory responses of Drosophila are encoded in the organization of projection neurons

K Choi, WK Kim, C Hyeon - Elife, 2022 - elifesciences.org
The projection neurons (PNs), reconstructed from electron microscope (EM) images of the
Drosophila olfactory system, offer a detailed view of neuronal anatomy, providing glimpses …

Olfactory cues in infant feeds: volatile profiles of different milks fed to preterm infants

M Muelbert, FH Bloomfield, S Pundir, JE Harding… - Frontiers in …, 2021 - frontiersin.org
Background: Smell is determined by odor-active volatile compounds that bind to specific
olfactory receptors, allowing us to discriminate different smells. Olfactory stimulation may …

Kinetic model for the desensitization of G protein-coupled receptor

WK Kim, Y Lee, SJ Jang, C Hyeon - The Journal of Physical …, 2024 - ACS Publications
Desensitization of G-protein-coupled receptors (GPCR) is a general regulatory mechanism
adopted by biological organisms against overstimulation of G protein signaling. Although the …

Unveiling the odor representation in the inner brain of Drosophila through compressed sensing

K Choi, WK Kim, C Hyeon - Physical Review Research, 2024 - APS
The olfaction begins when odorant molecules stimulate a finite number of receptor types in
the olfactory neurons. According to the recent connectomics data of the Drosophila olfactory …

General Chemical Reaction Network Theory for GPCR-based Olfactory Sensing: Elucidation of Odorant Mixture Effects and Agonist-Synergist Threshold

WK Kim, K Choi, C Hyeon, SJ Jang - arXiv preprint arXiv:2308.11936, 2023 - arxiv.org
This work presents a general chemical reaction network theory for olfactory sensing
processes that employ G-protein-coupled receptors as olfactory receptors (ORs). The theory …

Identification of the differences in olfactory system between male and female oriental tobacco budworm Helicoverpa assulta

H Li, W Li, C Miao, G Wang, M Zhao… - Archives of Insect …, 2021 - Wiley Online Library
The olfactory system of insects facilitates their search for host and mates, hence it plays an
essential role for insect survival and reproduction. Insects recognize odor substances …