Regenerating bone with bioactive glass scaffolds: A review of in vivo studies in bone defect models

AA El-Rashidy, JA Roether, L Harhaus, U Kneser… - Acta biomaterialia, 2017 - Elsevier
Large bone defects resulting from fractures and disease are a medical concern, being often
unable to heal spontaneously by the body's repair mechanisms. Bone tissue engineering …

Flourishing antibacterial strategies for osteomyelitis therapy

X Wang, M Zhang, T Zhu, Q Wei, G Liu… - Advanced …, 2023 - Wiley Online Library
Osteomyelitis is a destructive disease of bone tissue caused by infection with pathogenic
microorganisms. Because of the complex and long‐term abnormal conditions, osteomyelitis …

Quaternary ammonium-based biomedical materials: State-of-the-art, toxicological aspects and antimicrobial resistance

Y Jiao, L Niu, S Ma, J Li, FR Tay, J Chen - Progress in polymer science, 2017 - Elsevier
Microbial infections affect humans worldwide. Many quaternary ammonium compounds
have been synthesized that are not only antibacterial, but also possess antifungal, antiviral …

Membranes for guided bone regeneration: a road from bench to bedside

P Aprile, D Letourneur… - Advanced healthcare …, 2020 - Wiley Online Library
Bone resorption can negatively influence the osseointegration of dental implants. Barrier
membranes for guided bone regeneration (GBR) are used to exclude nonosteogenic tissues …

A review of the biomaterials technologies for infection-resistant surfaces

D Campoccia, L Montanaro, CR Arciola - Biomaterials, 2013 - Elsevier
Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Antibacterial coatings for titanium implants: Recent trends and future perspectives

S Akshaya, PK Rowlo, A Dukle, AJ Nathanael - Antibiotics, 2022 - mdpi.com
Titanium and its alloys are widely used as implant materials for biomedical devices owing to
their high mechanical strength, biocompatibility, and corrosion resistance. However, there is …

Biofilm formation in Staphylococcus implant infections. A review of molecular mechanisms and implications for biofilm-resistant materials

CR Arciola, D Campoccia, P Speziale, L Montanaro… - Biomaterials, 2012 - Elsevier
Implant infections in orthopaedics, as well as in many other medical fields, are chiefly
caused by staphylococci. The ability of growing within a biofilm enhances the chances of …

The complex relationship between virulence and antibiotic resistance

M Schroeder, BD Brooks, AE Brooks - Genes, 2017 - mdpi.com
Antibiotic resistance, prompted by the overuse of antimicrobial agents, may arise from a
variety of mechanisms, particularly horizontal gene transfer of virulence and antibiotic …

Therapeutic strategies to combat antibiotic resistance

BD Brooks, AE Brooks - Advanced drug delivery reviews, 2014 - Elsevier
With multidrug resistant bacteria on the rise, new antibiotic approaches are required.
Although a number of new small molecule antibiotics are currently in the development …

Anti-adhesive antimicrobial peptide coating prevents catheter associated infection in a mouse urinary infection model

K Yu, JCY Lo, M Yan, X Yang, DE Brooks… - Biomaterials, 2017 - Elsevier
Catheter-associated urinary tract infections (CAUTIs) represent one of the most common
hospital acquired infections with significant economic consequences and increased patient …