Respiratory viral infection-induced microbiome alterations and secondary bacterial pneumonia

S Hanada, M Pirzadeh, KY Carver… - Frontiers in …, 2018 - frontiersin.org
Influenza and other respiratory viral infections are the most common type of acute respiratory
infection. Viral infections predispose patients to secondary bacterial infections, which often …

Streptococcus pneumoniae's Virulence and Host Immunity: Aging, Diagnostics, and Prevention

LRK Brooks, GI Mias - Frontiers in immunology, 2018 - frontiersin.org
Streptococcus pneumoniae is an infectious pathogen responsible for millions of deaths
worldwide. Diseases caused by this bacterium are classified as pneumococcal diseases …

Generation and transmission of interlineage recombinants in the SARS-CoV-2 pandemic

B Jackson, MF Boni, MJ Bull, A Colleran… - Cell, 2021 - cell.com
We present evidence for multiple independent origins of recombinant SARS-CoV-2 viruses
sampled from late 2020 and early 2021 in the United Kingdom. Their genomes carry single …

Asplenia and spleen hypofunction

MV Lenti, S Luu, R Carsetti, F Osier… - Nature Reviews …, 2022 - nature.com
Asplenia (the congenital or acquired absence of the spleen) and hyposplenism (defective
spleen function) are common causes of morbidity and mortality. The spleen is a secondary …

Biofilm dispersal: multiple elaborate strategies for dissemination of bacteria with unique properties

C Guilhen, C Forestier, D Balestrino - Molecular microbiology, 2017 - Wiley Online Library
In most environments, microorganisms evolve in a sessile mode of growth, designated as
biofilm, which is characterized by cells embedded in a self‐produced extracellular matrix …

[HTML][HTML] Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization …

C Satzke, P Turner, A Virolainen-Julkunen, PV Adrian… - Vaccine, 2013 - Elsevier
Abstract In 2003 the World Health Organization (WHO) convened a working group and
published a set of standard methods for studies measuring nasopharyngeal carriage of …

Influenza promotes pneumococcal growth during coinfection by providing host sialylated substrates as a nutrient source

SJ Siegel, AM Roche, JN Weiser - Cell host & microbe, 2014 - cell.com
Much of the mortality attributed to influenza virus is due to secondary bacterial pneumonia,
particularly from Streptococcus pneumoniae. However, mechanisms underlying this …

Synergistic stimulation of type I interferons during influenza virus coinfection promotes Streptococcus pneumoniae colonization in mice

S Nakamura, KM Davis… - The Journal of clinical …, 2011 - Am Soc Clin Investig
Pneumococcal infection of the respiratory tract is often secondary to recent influenza virus
infection and accounts for much of the morbidity and mortality during seasonal and …

Carriage of Streptococcus pneumoniae and Other Respiratory Bacterial Pathogens in Low and Lower-Middle Income Countries: A Systematic Review and Meta …

RA Adegbola, R DeAntonio, PC Hill, A Roca, E Usuf… - PloS one, 2014 - journals.plos.org
Background Infection with Streptococcus pneumoniae is a major cause of childhood
morbidity and mortality worldwide, especially in low income countries where pneumococcal …

Streptococcus pneumoniae biofilm formation and dispersion during colonization and disease

Y Chao, LR Marks, MM Pettigrew… - Frontiers in cellular and …, 2015 - frontiersin.org
Streptococcus pneumoniae (the pneumococcus) is a common colonizer of the human
nasopharynx. Despite a low rate of invasive disease, the high prevalence of colonization …