Zonulin as a potential therapeutic target in microbiota-gut-brain axis disorders: encouraging results and emerging questions

A Veres-Székely, C Szász, D Pap, B Szebeni… - International journal of …, 2023 - mdpi.com
The relationship between dysbiosis and central nervous diseases has been proved in the
last 10 years. Microbial alterations cause increased intestinal permeability, and the …

The gut microbiota and celiac disease: Pathophysiology, current perspective and new therapeutic approaches

S Zoghi, A Abbasi, FS Heravi, MH Somi… - Critical Reviews in …, 2024 - Taylor & Francis
Celiac disease (CD) as a chronic gluten-sensitive intestinal condition, mainly affects
genetically susceptible hosts. The primary determinants of CD have been identified as …

Dexpanthenol exhibits antiapoptotic and anti‐inflammatory effects against nicotine‐induced liver damage by modulating Bax/Bcl‐xL, Caspase‐3/9, and Akt/NF‐κB …

N Üremiş, M Aslan, E Taşlidere… - Journal of Biochemical …, 2024 - Wiley Online Library
Chronic tobacco use can lead to liver damage and inflammation due to the accumulation of
various toxins in the body. This study aimed to investigate the correlation between the …

Tributyltin (TBT) toxicity: Effects on enteric neuronal plasticity and intestinal barrier of rats' duodenum

I Oliveira, GP Marinsek, LVB Correia… - Autonomic …, 2024 - Elsevier
Tributyltin (TBT) is a biocide used in the formulation of antifouling paints and it is highly
harmful. Despite the ban, the compound persists in the environment, contaminating marine …

Investigation of apoptotic effects of Cucurbitacin D, I, and E mediated by Bax/Bcl‐xL, caspase‐3/9, and oxidative stress modulators in HepG2 cell line

MM Üremiş, Y Türköz, N Üremiş - Drug Development Research, 2024 - Wiley Online Library
Cucurbitacins, natural compounds highly abundant in the Cucurbitaceae plant family, are
characterized by their anticancer, anti‐inflammatory, and hepatoprotective properties. These …

Ameliorative Effects of Larazotide Acetate on Intestinal Permeability and Bacterial Translocation in Acute Pancreatitis Model in Rats

D Karahan, MMM Harputluoglu, M Gul… - Digestive Diseases and …, 2024 - Springer
Background Intestinal barrier dysfunction in acute pancreatitis (AP) may progress to
systemic inflammatory response syndrome (SIRS) and multi-organ failures by causing …